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Leveraging BCMA-Directed Therapies for Improved Patient Outcomes in Relapsed/Refractory Multiple Myeloma
STATEMENT OF NEED
Multiple myeloma is a disease that remains incurable for most patients, many of whom become refractory to the majority of available treatments (Kumar et al, 2022). It is estimated that 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Agents targeting B-cell maturation antigen (BCMA), including antibody-drug conjugates (ADCs), chimeric antigen receptor (CAR) T-cell therapies, and bis... |
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Expert Guidance on Current Standards and New Directions in Newly Diagnosed Multiple Myeloma
STATEMENT OF NEED
An estimated 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Characterized by clonal proliferation of malignant plasma cells in the bone marrow, multiple myeloma is associated with anemia, renal insufficiency, bone destruction, and hypercalcemia, all of which significantly impact patients’ quality of life. The development of novel therapies and combinations in recent years, inclu... |
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Managing Immune Related Adverse Events to Ensure Optimal Cancer Immunotherapy Outcomes: The Nurse’s View
STATEMENT OF NEED
Immune checkpoint inhibitors, which alter immune regulatory pathways and promote cell-mediated destruction of tumor cells, have revolutionized the treatment of cancer in recent years, with numerous therapeutic agents approved and several targets under investigation (Chennamadhavuni et al, 2022). However, up to 90% of patients receiving immune checkpoint inhibitors experience immune-related adverse events, which can affect a wide variety of organ systems and can occur at any ... |
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The Role of the Clinical Pharmacist in the Management of Multiple Myeloma
Multiple myeloma (MM) is the second most common hematologic malignancy in the United States and is characterized by monoclonal proliferation of malignant plasma cells that accumulate within the bone marrow. The incidence of MM has increased in recent years, in part due to the revised definition of symptomatic MM from the International Myeloma Working Group in 2014. The National Cancer Institute estimated a total of 34,470 new cases in 2022, with 12,640 deaths. Despite significant advancements ... |
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Combining Locoregional and Systemic Therapy for Challenging HCC Cases
Target Audience
This educational activity is intended for interventional oncologyists physicians, nurses, and other members of the health care team who care for patients with hepatocellular carcinoma (HCC)
Program Overview
This activity focuses on challenges in the management of HCC using the latest clinical data supporting locoregional therapy, and on strategies for greater collaboration amongst the multidisciplinary teams in community vs academic settings.
Learning Objectives
Upon c... |
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NeuroRehabilitation 2024 - LIVE STREAMING
Comprehensive Neurorehabilitation Update
Cutting-edge strategies, updates, and best practices for state-of-the-art rehabilitation
In this course, which is among the highest-rated Harvard Medical School CME courses, many of the country’s most experienced and committed neurorehabilitation experts will present cutting-edge clinical interventions, the latest findings, practical education, and hands-on methods to further your expertise in guiding your patients with stroke, SCI, TBI, brain t... |
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Is It Safe? Safety Surveillance through the Antiretroviral Pregnancy Registry
Is It Safe? Safety Surveillance through the Antiretroviral Pregnancy Registry
Release Date: June 2, 2023
Expiration Date: June 2, 2024
Estimated Time to Complete: 1.25 hour
VIEW ACTIVITY
Clinical Gap and Educational Need
Antiretroviral therapy should be initiated for all persons with HIV who are pregnant regardless of CD4 count according to current guidelines. There is often minimal data available to make recommendations, however, for use in pregnancy. One key consideration is... |
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Individualized Strategies for Relapsed/Refractory Multiple Myeloma: Navigating Complexity with BCMA-Targeted and Novel Bispecific Antibodies
The expanding armamentarium of therapies for R/R MM shifts therapy selection from an algorithmic approach to an individualized strategy that requires consideration of the nature of relapse, prior therapies, treatment-related toxicities, as well as patient comorbidities and preferences. With the introduction of novel bispecific antibodies, specialists must learn how to optimally sequence these therapies and manage adverse events. To help clinicians navigate this complexity, individualized educa... |
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Physical Assessment - A Certificate Training Workshop for Pharmacy Practitioners
As pharmacists expand their scope of practice under
new legislation (SB493), physical assessment is a key
skill necessary for advanced practice. This 21 hour
course will prepare the pharmacist to obtain a
history and perform a basic physical examination
that will enable them to assess and monitor drug
therapy. The course will employ written materials,
videos, lectures, demonstrations and hands on
practice and feedback
Objectives for Pharmacists
At the conclusion of the course the p... |
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Addressing Key Questions About BCMA-Targeted Therapy for Relapsed/Refractory Multiple Myeloma
ACTIVITY DESCRIPTION
Though treatment advances have improved outcomes for most patients, MM remains an incurable disease characterized by continuous relapse. However, the treatment landscape for relapsed/refractory MM (RRMM) has expanded in recent years, and patients who relapse and/or become refractory to initial therapies are benefiting from the increasing availability of a diverse range of novel agents, including B-cell maturation antigen (BCMA)"targeted immunotherapies. These agents ... |
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Across the Compendium: Practical Pathways to Integrate Bispecific Antibodies Into Care for Patients With Relapsed/Refractory Multiple Myeloma
As the armamentarium of therapies for relapsed/refractory multiple myeloma (R/R MM) expands, several factors, including previous therapy, treatment-related toxicity, and comorbidities must be considered as part of clinical decision making. To assist the multidisciplinary treatment team in these efforts, and ensure patients are receiving cutting-edge cancer care, this immersive digital practice guide highlights best practices, clinical pearls, and strategies to overcome pitfalls in the administ... |
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EBP/PBE: What Do I Do When There is No Evidence - Dr. Rik Lemoncello
This course provides learners with an understanding of the purpose, procedures, and limitations of evidence-based practice (EBP) in clinical decision-making applied to speech-language pathology. Participants will learn about the important role of practice-based evidence (PBE) and how it complements EBP to support management decisions for individual clients. Practical strategies and resources will be presented so that learners can implement course ideas immediately into practice. |
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iPods, iPads, & iPhones, Oh My! Cognitive Rehab - Dr. Rik Lemoncello
This course is for those professionals working in adult acute and sub-acute rehabilitation settings. (The apps can also apply to those working with preteen/teens in any setting) The course will review accessibility options on an iDevice to support adults with cognitive challenges, describe methods to provide reminders or prompts to adults with memory challenges and describe methods to support attention or executive functioning for adults with cognitive challenges. |
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Managing Speech and Swallowing with Trach/Ventilator Dependence - Rik Lemoncello, PhD, CCC-SLP
This workshop will provide SLPs with important information to understand, assess, and manage speech and swallowing challenges with adult patients who have tracheostomy tubes and/or use ventilators for respiratory support. Dr. Lemoncello will present in a dynamic format with hands-on demonstrations with tracheostomy tubes, ventilator circuits, and speaking valve placement. An adult living with a tracheostomy tube who uses a speaking valve and nighttime ventilator will also share her experiences... |
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Therapy Tidbits – May/June 2017
COURSE ABSTRACT
Therapy Tidbits – May/June 2017 is a 1-hour online continuing education (CE) course comprised of select articles from the May/June 2017 issue of The National Psychologist, a private, independent bi-monthly newspaper intended to keep mental health professionals informed about practice issues. The articles included in this course are:
Advocates in Field of Aging Hear Strong Call to Action - Highlights focus points of the ASA conference in March: critical social and politic... |
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Back to Basics: Typical Swallowing Physiology in Adults - Rik Lemoncello, PhD, CCC-SLP
This course will present current best information to help clinicians learn about typical aspects of oropharyngeal and esophageal swallowing in adults and older adults. This course is ideal for clinicians who need a refresher on typical adult swallowing, and is appropriate for SLP, OT, dietary, nursing, and other medical clinicians involved with interprofessional management of dysphagia. Information covered will include review of sensory and motor control of swallowing, timing and neurological ... |
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Clinical Swallowing Evaluation for Adults - Dr. Rik Lemoncello
This course will present current best information to help clinicians learn about conducting and interpreting a clinical swallowing evaluation for adults in typical medical settings. This course will not discuss specific diagnoses or complex conditions such as tracheostomy/ventilator dependence. This course is ideal for clinicians who need a refresher on the purpose, procedures, observable signs/symptoms, and nature of recommendations that result from a clinical swallowing evaluation for adult ... |
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Mindfulness: The Healing Power of Compassionate Presence
Mindfulness: The Healing Power of Compassionate Presence is a 6-hour online continuing education (CE) course that will give you the mindfulness skills necessary to work directly, effectively, and courageously with your own and your clients' struggles.
Compassion towards others starts with compassion towards self. Practicing mindfulness cultivates our ability to pay intentional attention to our experience from moment to moment. Mindfulness teaches us to become patiently and spaciously aware ... |
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