Leveraging BCMA-Directed Therapies for Improved Patient Outcomes in Relapsed/Refractory Multiple Myeloma
STATEMENT OF NEED
Multiple myeloma is a disease that remains incurable for most patients, many of whom become refractory to the majority of available treatments (Kumar et al, 2022). It is estimated that 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Agents targeting B-cell maturation antigen (BCMA), including antibody-drug conjugates (ADCs), chimeric antigen receptor (CAR) T-cell therapies, and bis... |
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Warm Autoimmune Hemolytic Anemia (wAIHA)
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing people with wAIHA are largely based on case series and retrospective studies involving off-label medications. Also, while there are currently no medications specifically approved to treat wAIHA, data are emerging on new... |
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Hitting the Target in HER2-Positive Metastatic Colorectal Cancer
STATEMENT OF NEED
An estimated 153,020 new cases of colorectal cancer (CRC) are diagnosed annually, and 52,550 people die of the disease (Siegel et al, 2023). Approximately 22% of patients present with metastatic disease, which is associated with a dismal 5-year survival rate of 15% (SEER, 2022). Targeting biomarkers is a key strategy for expanding therapeutic options and improving outcomes in metastatic CRC. Human epidermal growth factor receptor 2 (HER2) amplification status and treatment... |
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Building and Maintaining a Multidisciplinary Team for Lysosomal Disorders
This CME/CE activity with Drs. Ozlem Goker-Aplan and Walla Al-Hertani describes the importance of a multidisciplinary team approach to managing lysosomal diseases, as well as some of the challenges involved in creating and maintaining that team.
At the end of this activity, participants should be able to:
- Describe the need for a team approach to care
- Describe best practices to build a multidisciplinary team for a new patient
- Describe best practices to maintain a multidisciplinary... |
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Expert Guidance on Current Standards and New Directions in Newly Diagnosed Multiple Myeloma
STATEMENT OF NEED
An estimated 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Characterized by clonal proliferation of malignant plasma cells in the bone marrow, multiple myeloma is associated with anemia, renal insufficiency, bone destruction, and hypercalcemia, all of which significantly impact patients’ quality of life. The development of novel therapies and combinations in recent years, inclu... |
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Myasthenia Gravis Research Highlights: AAN 2023
This 30-minute CME program highlights the latest clinical research about myasthenia gravis, a rare, autoimmune disease that targets the neuromuscular junction.
Treatment of myasthenia gravis is highly individualized and depends greatly on the myasthenia gravis subtype of each patient as well as each patient’s comorbidities. There are currently four drugs approved by the FDA, eculizumab, efgartigimod, ravulizumab, and rozanolixizumab. There are also treatments in development. Clinical tria... |
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Leveraging the Growing Arsenal of Adjuvant Therapies for Early-Stage NSCLC
In this activity, Dr. Helena A. Yu, Associate Attending Physician at Memorial Sloan Kettering Cancer Center, will provide insights into strategies for leveraging the growing arsenal of adjuvant therapies for early-stage non"small cell lung cancer (NSCLC), including treatment selection and adverse event management. Start the activity now!
STATEMENT OF NEED
Lung cancer is the second most commonly diagnosed cancer and the leading cause of death for men and women worldwide. In the Unite... |
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Pathology and Oncology Expert Perspectives in the Management of Triple-Negative Breast Cancer: Case Explorations and Answers to FAQs
STATEMENT OF NEED
Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for approximately 10% to 15% of breast cancer diagnoses and is characterized by the absence of estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2 (HER2). TNBC is more common in Black women and in women under the age of 40 (ACS, 2023). Compared with other subtypes of invasive breast cancer, TNBC has high rates of metastasis and a poor prognosis. Due to the lack ... |
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Virtual Tumor Board: Multidisciplinary Management of Advanced Soft Tissue Sarcoma
STATEMENT OF NEED
Sarcomas, which represent 1% to 2% of adult cancers, are a rare, heterogeneous group of neoplasms originating in the connective tissue. Soft tissue sarcomas, which begin in the muscle, tendons, fat, lymph, blood vessels, and nerves, encompass more than 80 histological subtypes. Approximately 25% of patients develop metastatic disease after curative-intent surgery, and for these patients, treatment options are limited and prognosis is very poor. In recent decades, the ident... |
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Putting the Freeze on Cold Agglutinin Disease
STATEMENT OF NEED
Cold agglutinin disease (CAD) is a rare subtype of autoimmune hemolytic anemia (AIHA) in which antibodies cause hemolysis at cold temperatures, generally between 37º to 39º Fahrenheit. Approximately 1 in a million people are affected by CAD annually, with onset usually occurring between the ages of 40 and 80 years. Individuals commonly experience fatigue, dizziness, palpitations, and shortness of breath caused by the anemia; jaundice caused by degradation of hemoglobin i... |
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Managing Patients with Rheumatic Disorders in Primary Care
Rheumatic disorders are prevalent, yet their diagnosis and treatment in affected patients are frequently challenging, contributing to a considerable disease burden. Ensuring timely intervention is critical to slow disease progression and improve patient outcomes. However, various educational gaps impede primary care clinicians from effectively achieving these goals. This 0.75-hour text-based activity features 3 modules comprised of 12 questions encountered in the primary care management of pat... |
Infection Control OSHA Focus | Accredited all 50 states | #1 Bestseller for Dental License Renewal | Dentists, Hygienists, Assistants
Online CE | Dental Infection Control OSHA Focus MyDentalCE.com | All 50 states 2023-2024. Meets state dental board requirements in all 50 states for 2 credit hours of instruction for license renewal in infection control and bloodborne pathogen review. Includes current information from OSHA, CDC, and various board updates. Reviews bloodborne pathogens, PPE, sterilization technique, chain of infection control, current topics like immunization and waste disposal, lists resources for the office, ... |
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Managing Cardiomyopathies in Lysosomal Disorders
This CME/CE activity describes the pathophysiologies and management options for lysosomal disease patients with cardiomyopathies.
At the end of this activity, participants should be able to:
- Describe the role of the cardiologist in the team approach to care
- Describe best practices to monitor cardiac symptoms in lysosomal disorders
- Describe best practices to treat cardiac symptoms in lysosomal disorders |
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Acromegaly Research Highlights: ENDO 2023
This 30-minute CME-accredited program highlights the latest clinical research about acromegaly, a rare endocrine disorder. Common symptoms include subtle skeletal overgrowth; soft tissue swelling (tongue, heart, kidney, colon, and vocal cords); unusually prominent forehead and heavy brow ridge; protruding lower jaw; overbite; skin thickening; increased shoe and ring size; hypertension; increased perspiration; headaches; paresthesia; and sexual dysfunction.
There are several orphan drugs app... |
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Managing Immune Related Adverse Events to Ensure Optimal Cancer Immunotherapy Outcomes: The Nurse’s View
STATEMENT OF NEED
Immune checkpoint inhibitors, which alter immune regulatory pathways and promote cell-mediated destruction of tumor cells, have revolutionized the treatment of cancer in recent years, with numerous therapeutic agents approved and several targets under investigation (Chennamadhavuni et al, 2022). However, up to 90% of patients receiving immune checkpoint inhibitors experience immune-related adverse events, which can affect a wide variety of organ systems and can occur at any ... |
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Cushing’s Disease Research Highlights: ENDO 2023
This 30-minute CME program highlights the latest clinical research about Cushing’s disease.
Cushing’s disease is caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary tumor that leads to excessive levels of cortisol.
This CME program, hosted by Lisa Machtigall, MD, Clinical Director, Neuroendocrine & Pituitary Tumor Clinical Center at Massachusetts General Hospital, and Associate Professor of Medicine at Harvard Medical School, provides an overview of the latest cli... |
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New Guidance to Diagnose and Treat Tumor-induced Osteomalacia (TIO)
This 30-minute CME-accredited program, hosted by Aliya Khan, MD, Clinical Professor of Medicine at McMaster University, highlights the best practices to diagnose and treat tumor induced osteomalacia (TIO) based on the recently published global guidance document in the Journal of Internal Medicine.
This activity has been designed to meet the educational needs of physicians specializing in neurology, orthopedics, internal medicine/general practice, rheumatology, endocrinology, pain management... |
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Myasthenia Gravis and the Complement System
This 45-minute CME-accredited program, hosted by James F Howard Jr, MD, Professor of Neurology, Medicine & Allied Health at The University of North Carolina at Chapel Hill, highlights the connection between the complement system and myasthenia gravis in regards to the pathophysiology and treatment of this rare disease.
After participating in the activity, learners should be better able to:
- Review the pathophysiology of MG.
- Describe the role of the complement system in MG.
- Descr... |
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Assessing, Monitoring, and Managing Respiratory Involvement in Lysosomal Disorders
Ozlem Gore-Alpan, MD of LDRTC and John Bach, MD, Professor of Neurology at Rutgers School of Medicine discuss best practices to manage respiratory complications in persons with lysosomal disorders.
At the end of this activity, participants should be able to:
- Describe the most common LSDs that have pulmonary complications.
- Describe best practices to manage pulmonary symptoms in Pompe disease.
- Describe best practices to manage pulmonary symptoms in MPSs.
- Describe best practices to... |
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MyDentalCE.com | Online Dental CE for Dentists, Hygienists, Assistants | #1 Rated in Prompt Customer Service | Instant Certificate upon Course Completion
Affordable Online CE courses for Dentists, Hygienists, and Assistants | Instant Completion Certificate | OSHA and regulatory training in Infection Control ,Bloodborne Pathogens, Hazard Communication, HIPAA, Radiography Review and many new and current courses. Packages and group discounts available. #1 in Customer Service for Online Self Study | CEsupport@mydentalce.com Customer service hotline: (530) 238-5333. Questions welcome! |
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Ohio Dental Radiography Review for Dental Assistants 2023-24 | 2 CEs Updated | Certificate Renewal & all 50 states | AGD PACE recognized provider | Affordable & Fast
Ohio Radiography Review for Dental Assistants (Ohio for certificate renewal). Take MyDentalCE.com online review course and get an instant certificate upon completion. This updated for 2023-24 Radiography Review for dental assistants is designed for the license renewal board requirements in Ohio as well as any other state in the US. The course is a straightforward review of dental assistant radiography principles. Academy of General Dentistry PACE #373218 recognized provider in all 50 states in... |
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California Dental CE Online | $99 for 25 CEs | MyDentalCE.com | Board Approved Infection Control & Dental Practice Act & Opioid Required course | 2022-24
25 CEs | $99. For California dentists including Cal OSHA Infection Control, California Dental Practice Act (both mandatory & board approved for 2023-2024), board newly approved Opioid Responsibilities, and Bloodborne Pathogens Standard Review. We also can do course substitutions & we offer group discounts. Immediately upon purchase, we send you links to the PDF course files with instructions and all the course download links. The examination links easily accessible in each course. Un... |
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OSHA Annual Review Training for Dental Staff with Interactive Videos - "New Hire" Training | Includes IC, BBP, HazCom, HIPAA Intro
New Dental OSHA Annual & New Hire Training with HIPAA introduction + Respectful Workplace. The format is a blend of text and videos located throughout the course. All updated topics including COVID's impact. Covers Infection Control, Bloodborne Pathogens, HazCom, HIPAA intro and provides resources, apps, and checklists.
You can choose form a "single" course and 3-5-10 packages. More than 20, contact our office for deep discounted quote. Instant completion certificate. The s... |
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California Opioid Prescribers: Responsibilities and Requirements | Board Approved Mandated Course
On January 1, 2023, the Dental Board of California (DBC) and CA Law mandated that all Schedule II Opioid prescribers, including dentists, take a dental board approved course to fulfill the CE mandate. This brand new text-based PDF file self-instruction course is based on explicit content guidelines issued by the DBC and the Calif Code of Regulations. This 2023-2024 DBC approved course covers best practices in pain management, resources for Substance Abuse Disorder, and the regulations, respons... |
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Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults
STATEMENT OF NEED
Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w... |
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Current Standards and New Directions in the Treatment of Acquired Thrombotic Thrombocytopenic Purpura
STATEMENT OF NEED
Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy with a rapid onset and progression and a mortality rate of 10% to 20% with prompt treatment. Onset of aTTP is characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and a constellation of associated symptoms including hemorrhage, neurologic and renal manifestations, cardiac abnormalities, and mesenteric ischemia (Joly et al, 2017). Survivors of f... |
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Recurrent and Metastatic HNSCC: New Insights and Real-World Evidence for Improved Patient Outcomes
STATEMENT OF NEED
Head and neck cancers represent a heterogeneous group of tumors that originate in the lip/oral cavity, hypopharynx, oropharynx, nasopharynx, and larynx. An estimated 66,470 new cases are diagnosed in the United States annually, and 15,050 people die of the disease (Siegel et al, 2022). Approximately 90% of cases are classified as head and neck squamous cell carcinoma (HNSCC). Treatment of HNSCC is complicated by numerous factors, including differing therapeutic strategies ... |
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Exploring Novel Treatments for Rett Syndrome
STATEMENT OF NEED
Rett syndrome is a rare, debilitating neurodevelopmental disorder almost always associated with a spontaneous mutation in the methyl-CpG-binding protein 2 (MECP2) gene on the X-chromosome. Affected individuals experience loss of purposeful hand skills, abnormalities in gait, loss of spoken language, and stereotypic hand movements, with more severe manifestations including seizures, autistic features, autonomic nervous system dysfunction, breathing abnormalities, sleep dist... |
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Best Practices in Nursing Management of Chemotherapy-Induced Peripheral Neuropathy
STATEMENT OF NEED
Chemotherapy-induced peripheral neuropathy (CIPN) is a complication of cancer treatment that may impair quality of life and lead to dose reductions or discontinuation of treatment. In one study, among 105 patients receiving paclitaxel for breast cancer, 36.2% needed dose reductions due to CIPN (Timmins et al, 2021). Whereas in some patients the symptoms improve with time, in others, there is progression with permanent nerve damage (Zajączkowska et al, 2019). At present, the... |
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Sexual Harassment Prevention
Sexual Harassment (required CE by the State of Illinois) |
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Navigating pain management, safe opioid prescribing, and opioid use disorder
This program is presented in six thirty minute sessions that can be completed individually.
The sessions are:
Session 1: Pain Taxonomy, pathogenesis, and assessment
Session 2: Developing a patient-centered pain treatment plan
Session 3: Non-opioid analgesics: Evidence and clinical pearls
Session 4: Opioid analgesics: From A to Z
Session 5: Clinical use of opioids: Safe prescribing and appropriate monitoring
Session 6: The exit strategy: When the treatment becomes the ... |
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Operation Game- A Patient’s Journey Through HeFH: Diagnosis and Management
Target Audience
This activity has been designed to address the educational needs of cardiologists, cardiology nurses, lipid specialists, and primary care clinicians, including internists, pharmacists, nurses, nurse practitioners, PAs, and dietitians. It may also benefit other healthcare providers who manage patients with hypercholesterolemia.
Program Overview
Nonstatins are an essential therapy for lowering low-density lipoprotein cholesterol (LDL-C) levels in high-risk patients, such as ... |
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COVID-19 Vaccine Myth Busters (Technician)
Recommendations regarding COVID-19 immunizations are being updated frequently. This session will discuss the safety and efficacy data available for the COVID-19 vaccines that have received an Emergency Use Authorization (EUA) from the Food and Drug Administration (FDA). Included in the discussion will be the mechanism of action and a comparison of dosage, schedule, and storage for the available COVID-19 vaccines. Patient cases to review recommended vaccines based on patient-specific factors an... |
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COVID-19 Vaccine Myth Busters (Pharmacist)
Recommendations regarding COVID-19 immunizations are being updated frequently. This session will discuss the safety and efficacy data available for the COVID-19 vaccines that have received an Emergency Use Authorization (EUA) from the Food and Drug Administration (FDA). Included in the discussion will be the mechanism of action and a comparison of dosage, schedule, and storage for the available COVID-19 vaccines. Patient cases to review recommended vaccines based on patient-specific factors an... |
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Pulmonary and Critical Care Medicine 2024 - LIVE STREAMING
Comprehensive Updates for State-of-the-Art Evaluation, Diagnosis, and Treatment
This comprehensive live streaming online course, which is among the highest-rated Harvard Medical School CME courses, provides education and updates to optimize your care of patients with:
• Sepsis
• ARDS
• Sarcoidosis
• IPF
• Bronchiectasis
• Cystic fibrosis
• Lung nodules
• Lung cancer
• GERD
• Pleural disease
• Pneumonia
• Tuberculosis
• Thromboembolism
• Chronic cou... |
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Acromegaly: Improving Timely Diagnosis, Assessment, and Treatment
Acromegaly, caused by excessive growth hormone production from the anterior pituitary gland, results in disproportionate growth of body tissues and other metabolic dysfunctions. With causes divided into primary GH excess, ectopic or iatrogenic GH excess, and excess growth hormone-releasing hormone (GHRH), adult patients have the characteristic facial features of a large lower jaw, a prominent forehead, and large hands and feet. These features occur after the growth plates are fused, distinguis... |
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Advancing the Care of Patients Living with EGPA Through Multidisciplinary, Patient-Focused Care
Target Audience
This educational activity is intended for rheumatologists, allergists, immunologists, pulmonologists, and specialty advance practice clinicians who care for patients with EGPA.
Program Overview
The comprehensive program provides up-to-date information regarding EGPA"its recognition, diagnosis, and treatment"and incorporates the patient perspective to raise awareness of patients’ needs, heighten urgency, and, ultimately, educate on the disease. The program will ... |
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The Safety of Opioid Use in Chronic Obstructive Pulmonary Disease
This session will evaluate the safety of opioid therapy among patients with chronic obstructive pulmonary disease (COPD). The session will cover existing safety and effectiveness evidence from clinical trials, and present the latest data from observational studies. The presentation will include a discussion of the strengths and disadvantages of observational study designs along with implications for future practice.
Approximately 15.7 million Americans (6.4%) currently are diagnosed with CO... |
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Right Treatment, Right Patient: Evidence-Based Approaches to the Treatment of Moderate-to-Severe Atopic Dermatitis Snippet 1: Currently Available Injectable Biologic Therapies for Moderate-to-Severe Atopic Dermatitis (AD)
Target Audience
This activity is designed to meet the educational needs of dermatology and allergy physicians, nurse practitioners, PAs, and nurses who care for patients with moderate-to-severe atopic dermatitis.
Program Overview
This activity features a case presentation, a brief overview of currently available injectable biologic therapies, and insights from an expert faculty.
Learning Objectives
After completing this activity, the participant should be better able to::
Identify ... |
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Opioids Overview & Guidelines for Dentists | Pain Management (3 CEs)
Opioids Overview & Guidelines for Dentists | Pain Management Review 3 CE / Credit Hours
Sources/Editor/Author:
MaryLou Austin, RDH, MS, Health Science Editor
Michelle Jameson, MA, Science Editor
Public Domain Information - CDC, NIH, HHS, Washington Medical Agencies, ADA Opioid Policies, et al. Bree Collaborative
Learning Objectives:
*Know the principles of pain management for acute pain in dental patients.
*Understand the mechanisms of opioid agonists an... |
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Infectious Diseases in Adults 2024 - LIVE STREAMING
State-of-the-art approaches to prevention, diagnosis, and treatment of infectious diseases
This comprehensive Harvard Medical School CME program"one of the highest-rated HMS CME courses"ensures attendees are current with state-of-the-art approaches to prevention, detection, diagnosis, and treatment of infectious diseases. Updates, best practices and new guidelines are presented by nationally recognized ID experts and master clinicians. Education is practical and results driven:
... |
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Ace the Case: A 47-Year-Old Man With Oral Corticosteroid-Dependent Asthma
This educational activity will utilize a case study to discuss a 47-year-old man with oral corticosteroid"dependent asthma. |
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Ace the Case: A 34-Year-Old Woman With Painful Swallowing
This educational activity will utilize a case study to discuss a 34-year-old woman with painful swallowing that has been progressively worsening for the past few days and is associated with anorexia, nausea, and epigastric abdominal pain. |
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Ace the Case: A 62-Year-Old Woman With Unintentional Weight Loss of 20 Pounds
This educational activity will utilize a case study to discuss a 62-year-old woman with a 20-pound unintentional weight loss and recurrent emesis over the past 3 months. |
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nAMD and DME Management: Rapid Response From ARVO
Real-world outcomes with anti-vascular endothelial growth factor (VEGF) therapies in the management of patients with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) are often not comparable to those of clinical studies. Discrepancies in these outcomes have been associated with undertreatment due to high treatment burden and the associated loss of patient adherence to dosing schedules. Newer therapies with novel mechanisms that extend intervals between dosing... |
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nAMD and DME Management: Rapid Response From ARVO
Real-world outcomes with anti-vascular endothelial growth factor (VEGF) therapies in the management of patients with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) are often not comparable to those of clinical studies. Discrepancies in these outcomes have been associated with undertreatment due to high treatment burden and the associated loss of patient adherence to dosing schedules. Newer therapies with novel mechanisms that extend intervals between dosing... |
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Pediatric Immunizations Should Not Be a Sticking Point
The goal of this CE presentation is to educate licensed pharmacists on pediatric immunization schedules, proper administration, and provide resources/tools to overcome pediatric vaccine hesitancy. By the end of this program, pharmacists will successfully have completed two hours of immunization-related CE in accordance with U.S. Department of Health & Human Services (HHS) requirements. This program is a recorded webinar originally presented in March 2021. |
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Pediatric Immunizations Should Not Be a Sticking Point
The goal of this CE presentation is to educate licensed pharmacists on pediatric immunization schedules, proper administration, and provide resources/tools to overcome pediatric vaccine hesitancy. By the end of this program, pharmacists will successfully have completed two hours of immunization-related CE in accordance with U.S. Department of Health & Human Services (HHS) requirements. This program is a recorded webinar originally presented in March 2021. |
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Real-World Perspectives in Managing CLL Treatment
Management options for chronic lymphocytic leukemia (CLL) have expanded in recent years. The emergence of new immunotherapeutic and targeted agents for both the first-line and relapsed/refractory settings"though of course beneficial for CLL patients"represents a challenge to clinicians, who must navigate the indicated uses, mechanisms of action, and toxicity profiles of these new agents. In determining optimal treatment plans, clinicians are also confronted with significant advances ... |
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May 16-18, 2024 Update CME Internal Medicine and Primary Care Conference
Eminent speakers from The University of Chicago, Northwestern University, The University of Illinois Chicago, and Rush University will provide comprehensive updates on the latest clinical guidelines.
Target Audience: Internal Medicine, Primary Care, Family Medicine, and Hospitalist Medicine Physicians, Nurse Practitioners, and Physician Assistants
Earn 25 CME Credits
This activity has been approved for AMA PRA Category 1 Credit™️.
This activity has been approved for AAFP Prescribe... |