Warm Autoimmune Hemolytic Anemia (wAIHA)
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing people with wAIHA are largely based on case series and retrospective studies involving off-label medications. Also, while there are currently no medications specifically approved to treat wAIHA, data are emerging on new... |
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Hitting the Target in HER2-Positive Metastatic Colorectal Cancer
STATEMENT OF NEED
An estimated 153,020 new cases of colorectal cancer (CRC) are diagnosed annually, and 52,550 people die of the disease (Siegel et al, 2023). Approximately 22% of patients present with metastatic disease, which is associated with a dismal 5-year survival rate of 15% (SEER, 2022). Targeting biomarkers is a key strategy for expanding therapeutic options and improving outcomes in metastatic CRC. Human epidermal growth factor receptor 2 (HER2) amplification status and treatment... |
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Expert Guidance on Current Standards and New Directions in Newly Diagnosed Multiple Myeloma
STATEMENT OF NEED
An estimated 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Characterized by clonal proliferation of malignant plasma cells in the bone marrow, multiple myeloma is associated with anemia, renal insufficiency, bone destruction, and hypercalcemia, all of which significantly impact patients’ quality of life. The development of novel therapies and combinations in recent years, inclu... |
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Virtual Tumor Board: Multidisciplinary Management of Advanced Soft Tissue Sarcoma
STATEMENT OF NEED
Sarcomas, which represent 1% to 2% of adult cancers, are a rare, heterogeneous group of neoplasms originating in the connective tissue. Soft tissue sarcomas, which begin in the muscle, tendons, fat, lymph, blood vessels, and nerves, encompass more than 80 histological subtypes. Approximately 25% of patients develop metastatic disease after curative-intent surgery, and for these patients, treatment options are limited and prognosis is very poor. In recent decades, the ident... |
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Putting the Freeze on Cold Agglutinin Disease
STATEMENT OF NEED
Cold agglutinin disease (CAD) is a rare subtype of autoimmune hemolytic anemia (AIHA) in which antibodies cause hemolysis at cold temperatures, generally between 37º to 39º Fahrenheit. Approximately 1 in a million people are affected by CAD annually, with onset usually occurring between the ages of 40 and 80 years. Individuals commonly experience fatigue, dizziness, palpitations, and shortness of breath caused by the anemia; jaundice caused by degradation of hemoglobin i... |
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Managing Immune Related Adverse Events to Ensure Optimal Cancer Immunotherapy Outcomes: The Nurse’s View
STATEMENT OF NEED
Immune checkpoint inhibitors, which alter immune regulatory pathways and promote cell-mediated destruction of tumor cells, have revolutionized the treatment of cancer in recent years, with numerous therapeutic agents approved and several targets under investigation (Chennamadhavuni et al, 2022). However, up to 90% of patients receiving immune checkpoint inhibitors experience immune-related adverse events, which can affect a wide variety of organ systems and can occur at any ... |
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Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults
STATEMENT OF NEED
Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w... |
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Current Standards and New Directions in the Treatment of Acquired Thrombotic Thrombocytopenic Purpura
STATEMENT OF NEED
Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy with a rapid onset and progression and a mortality rate of 10% to 20% with prompt treatment. Onset of aTTP is characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and a constellation of associated symptoms including hemorrhage, neurologic and renal manifestations, cardiac abnormalities, and mesenteric ischemia (Joly et al, 2017). Survivors of f... |
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Exploring Novel Treatments for Rett Syndrome
STATEMENT OF NEED
Rett syndrome is a rare, debilitating neurodevelopmental disorder almost always associated with a spontaneous mutation in the methyl-CpG-binding protein 2 (MECP2) gene on the X-chromosome. Affected individuals experience loss of purposeful hand skills, abnormalities in gait, loss of spoken language, and stereotypic hand movements, with more severe manifestations including seizures, autistic features, autonomic nervous system dysfunction, breathing abnormalities, sleep dist... |
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Operation Game- A Patient’s Journey Through HeFH: Diagnosis and Management
Target Audience
This activity has been designed to address the educational needs of cardiologists, cardiology nurses, lipid specialists, and primary care clinicians, including internists, pharmacists, nurses, nurse practitioners, PAs, and dietitians. It may also benefit other healthcare providers who manage patients with hypercholesterolemia.
Program Overview
Nonstatins are an essential therapy for lowering low-density lipoprotein cholesterol (LDL-C) levels in high-risk patients, such as ... |
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Pulmonary and Critical Care Medicine 2024 - LIVE STREAMING
Comprehensive Updates for State-of-the-Art Evaluation, Diagnosis, and Treatment
This comprehensive live streaming online course, which is among the highest-rated Harvard Medical School CME courses, provides education and updates to optimize your care of patients with:
• Sepsis
• ARDS
• Sarcoidosis
• IPF
• Bronchiectasis
• Cystic fibrosis
• Lung nodules
• Lung cancer
• GERD
• Pleural disease
• Pneumonia
• Tuberculosis
• Thromboembolism
• Chronic cou... |
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Acromegaly: Improving Timely Diagnosis, Assessment, and Treatment
Acromegaly, caused by excessive growth hormone production from the anterior pituitary gland, results in disproportionate growth of body tissues and other metabolic dysfunctions. With causes divided into primary GH excess, ectopic or iatrogenic GH excess, and excess growth hormone-releasing hormone (GHRH), adult patients have the characteristic facial features of a large lower jaw, a prominent forehead, and large hands and feet. These features occur after the growth plates are fused, distinguis... |
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The Safety of Opioid Use in Chronic Obstructive Pulmonary Disease
This session will evaluate the safety of opioid therapy among patients with chronic obstructive pulmonary disease (COPD). The session will cover existing safety and effectiveness evidence from clinical trials, and present the latest data from observational studies. The presentation will include a discussion of the strengths and disadvantages of observational study designs along with implications for future practice.
Approximately 15.7 million Americans (6.4%) currently are diagnosed with CO... |
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nAMD and DME Management: Rapid Response From ARVO
Real-world outcomes with anti-vascular endothelial growth factor (VEGF) therapies in the management of patients with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) are often not comparable to those of clinical studies. Discrepancies in these outcomes have been associated with undertreatment due to high treatment burden and the associated loss of patient adherence to dosing schedules. Newer therapies with novel mechanisms that extend intervals between dosing... |
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nAMD and DME Management: Rapid Response From ARVO
Real-world outcomes with anti-vascular endothelial growth factor (VEGF) therapies in the management of patients with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) are often not comparable to those of clinical studies. Discrepancies in these outcomes have been associated with undertreatment due to high treatment burden and the associated loss of patient adherence to dosing schedules. Newer therapies with novel mechanisms that extend intervals between dosing... |
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May 16-18, 2024 Update CME Internal Medicine and Primary Care Conference
Eminent speakers from The University of Chicago, Northwestern University, The University of Illinois Chicago, and Rush University will provide comprehensive updates on the latest clinical guidelines.
Target Audience: Internal Medicine, Primary Care, Family Medicine, and Hospitalist Medicine Physicians, Nurse Practitioners, and Physician Assistants
Earn 25 CME Credits
This activity has been approved for AMA PRA Category 1 Credit™️.
This activity has been approved for AAFP Prescribe... |
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Introduction to Musculoskeletal Ultrasound - Blended
The Blended Introduction to Musculoskeletal Ultrasound Training Course provides participants a comprehensive introduction to upper and lower extremity musculoskeletal ultrasound for diagnostic applications and ultrasound guided injection/aspiration techniques. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading musculoskeletal ultrasound experts, the online course incorporates comprehensive lectu... |
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Introduction to Musculoskeletal Ultrasound with Interventional Human Cadaver Lab - Blended
The Blended Introduction to Musculoskeletal Ultrasound with Interventional Cadaver Lab Training Course provides participants a comprehensive introduction to upper and lower extremity musculoskeletal ultrasound for diagnostic applications and ultrasound guided injection/aspiration techniques. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading musculoskeletal ultrasound experts, the online course ... |
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Peripheral Nerve Ultrasound - Blended
The Blended Peripheral Nerve Ultrasound Course is designed to provide a comprehensive approach to the use of ultrasound for the assessment and treatment of peripheral nerves. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading peripheral nerve and musculoskeletal ultrasound experts, the online course incorporates a comprehensive review of the sonographic appearance and recognition of upper and lo... |
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Peripheral Nerve Ultrasound with Interventional Human Cadaver Lab - Blended
The Blended Peripheral Nerve Ultrasound with Interventional Cadaver Lab Training Course is designed to provide a comprehensive approach to the use of ultrasound for the assessment and treatment of peripheral nerves. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading peripheral nerve and musculoskeletal ultrasound experts, the online course incorporates a comprehensive review of the sonographic a... |
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The Role of the Clinical Pharmacist in the Management of Multiple Myeloma
Multiple myeloma (MM) is the second most common hematologic malignancy in the United States and is characterized by monoclonal proliferation of malignant plasma cells that accumulate within the bone marrow. The incidence of MM has increased in recent years, in part due to the revised definition of symptomatic MM from the International Myeloma Working Group in 2014. The National Cancer Institute estimated a total of 34,470 new cases in 2022, with 12,640 deaths. Despite significant advancements ... |
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Geographic Atrophy: Rapid Response from ARVO
Geographic atrophy (GA) is a pathological deterioration of the retina seen in the late stages of age-related macular degeneration (AMD). It affects 20% of people with AMD, and its prevalence increases exponentially with age. Until recently, there were no treatment options for GA, but investigation into the complement system and its role in the pathogenesis of GA has led to targeted therapies that have revolutionized the treatment paradigm. Because of the recent approval of one of these therapi... |
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Parkinson’s Disease " Updates in Diagnosis and Patient Management
Parkinson's disease is a neurodegenerative disorder, second only in prevalence to Alzheimer’s disease. Numerous therapeutic options, including carbidopa/levodopa, monoamine oxidase-B inhibitors, dopamine agonists, and device-assisted therapies, are available for treatment. These treatments are indicated at different stages following diagnosis. However, Parkinson’s disease progresses at highly variable rates, and no biomarkers, laboratory tests, or gold standard indexes are available t... |
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Case Challenges in nAMD and DME Management: Achieving Durable Response
The management of diabetic macular edema (DME) and neovascular age-related macular degeneration (nAMD) with intravitreal anti-vascular endothelial growth factor (VEGF) therapies has provided enhanced visual outcomes for many patients. However, the high treatment burden associated with anti-VEGF therapies can lead to lack of patient adherence, resulting in suboptimal outcomes. Personalized treatment protocols using FDA-approved agents and newer novel delivery systems, along with agents with uni... |
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Warm Autoimmune Hemolytic Anemia (wAIHA)
Target Audience
This activity has been designed to meet the educational needs of physicians specializing in hematology and hematology-oncology. Other members of the care team may also participate.
Program Overview
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing ... |
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Innovations and New Practices in Internal Medicine 2024 -LIVE STREAMING
The State of the Art in Internal Medicine
This program, which is among the highest-rated Harvard Medical School CME courses, provides a comprehensive update of the most important changes now impacting Internal Medicine and guidance on how to incorporate these changes into your clinical practice to improve patient outcomes..
Practical, Fast-Paced, Online Education
This live streaming educational experience is fast paced, relevant to the current healthcare environment, and draws upon real... |
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Sports Medicine 2024 -LIVE STREAMING
The Comprehensive 2024 Sports Medicine Update
State-of-the-Art Approaches to the Diagnosis, Treatment, Rehabilitation, and Prevention of Sports Injuries
This Harvard Medical School CME program, which is among the highest-rated HMS CME courses, provides a special and timely opportunity to hear directly from world-renowned physician specialists (physiatrists, orthopedists, radiologists), team physicians and athletic trainers for the Boston Red Sox, New England Revolution, and New England P... |
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Optimizing Outcomes in ALS: Best Practices in Screening, Diagnosis, and Treatment
"Optimizing Outcomes in ALS: Best Practices in Screening, Diagnosis, and Treatment" is a modular continuing education series led by Dr. Richard Bedlack, a nationally recognized ALS expert. This self-navigation program focuses on amyotrophic lateral sclerosis (ALS), providing healthcare professionals with valuable insights and evidence-based strategies to enhance outcomes in ALS care. Participants have the flexibility to choose their own track and explore various modules, covering cli... |
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NeuroRehabilitation 2024 - LIVE STREAMING
Comprehensive Neurorehabilitation Update
Cutting-edge strategies, updates, and best practices for state-of-the-art rehabilitation
In this course, which is among the highest-rated Harvard Medical School CME courses, many of the country’s most experienced and committed neurorehabilitation experts will present cutting-edge clinical interventions, the latest findings, practical education, and hands-on methods to further your expertise in guiding your patients with stroke, SCI, TBI, brain t... |
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Introduction to Carotid & Peripheral Vascular Duplex/Color Flow Ultrasound - Blended
The Combined Blended Introduction to Carotid and Peripheral Vascular Duplex/Color Flow Imaging Course will give you a strong foundation to begin performing and/or interpreting Carotid and Peripheral Vascular and Indirect PV Ultrasound Examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online courses: Receive fifteen (15) months unlimited access to two (2) comprehensive online courses taught by leading ... |
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Introduction to Abdominal and Primary Care Ultrasound - Blended
The Blended Introduction to Abdominal & Primary Care Ultrasound course will give you a strong foundation to begin performing and/or interpreting abdominal and point-of-care ultrasound. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading abdominal and primary care ultrasound experts, the comprehensive online course covers liver, gallbladder/biliary tree, renal/bladder, pancreas, sp... |
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Introduction to Adult Echocardiography - Blended
The Blended Introduction to Adult Echocardiography Course will give you a strong foundation to begin performing and/or interpreting comprehensive adult cardiac examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading echocardiography experts, the comprehensive online course covers cardiac anatomy & physiology, 2D & M-mode scan techniques cardiac Doppler principles, ev... |
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Introduction to Carotid Duplex/Color Flow & Transcranial Doppler Ultrasound - Blended
The Combined Blended Introduction to Carotid Duplex/Color Flow Imaging and Transcranial Doppler Ultrasound Courses will give you a strong foundation to begin performing and/or interpreting Carotid and Transcranial Doppler Ultrasound Examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online courses: Receive fifteen (15) months unlimited access to two (2) comprehensive online courses taught by leading va... |
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Introduction to Carotid Duplex/Color Flow Ultrasound - Blended
The Blended Introduction to Carotid Duplex/Color Flow Imaging Course will give you a strong foundation to begin performing and/or interpreting Carotid Ultrasound Examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading vascular ultrasound experts, the comprehensive online course covers cerebrovascular anatomy& physiology, Doppler principles, scan techniques, and interpret... |
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Introduction to Transcranial Doppler Ultrasound - Blended
The Blended Introduction to Transcranial Doppler Ultrasound course will give you a strong foundation to begin performing and/or interpreting transcranial Doppler examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading vascular ultrasound experts, the online course provides a comprehensive review of neuro-anatomy, normal and abnormal Doppler waveform characteristics, and scan... |
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Introduction to Peripheral Vascular Duplex/Color Flow Ultrasound - Blended
The Blended Introduction to Peripheral Vascular Duplex/Color Flow Imaging Course will give you a strong foundation to begin performing and/or interpreting Peripheral Vascular Duplex/Color Flow Imaging and Indirect PV Ultrasound Examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading vascular ultrasound experts, the comprehensive online course covers peripheral arterial and v... |
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Disparities in Ovarian Cancer: Increasing Awareness to Improve Risk Assessment and Outcomes
Ovarian cancer is the most common cause of cancer death in women with gynecologic malignancy and the fifth leading cause of cancer death in the US. Although the incidence of ovarian cancer is higher among White women than Black women, studies have identified disparities in assessment, care and outcomes seen among Black women with ovarian cancer. It has been shown that outcomes in clinical oncology can be improved when care is delivered by high performance teams. This activity was designed by ... |
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In Case You Missed: Utilizing the Muscarinic System to Optimize Treatment Options for Schizophrenia
Schizophrenia is an incurable, neuropsychiatric disease characterized by difficulties thinking and communicating clearly as well as psychosis (ie, “positive” symptoms); difficulty functioning socially (ie, “negative” symptoms); and cognitive impairment. As many as 34% of patients with schizophrenia have treatment-resistant schizophrenia, defined as continuing symptoms despite at least 2 trials of appropriate antipsychotic treatment, and most people do not recover from it. Patients with... |
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Introduction and Advanced Emergency Medicine Ultrasound - Blended
The Blended Introduction & Advanced Emergency Medicine Ultrasound Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the core and advanced ultrasound applications as outlined in the ACEP, ACGME, and WINFOCUS ultrasound practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the s... |
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Introduction and Advanced Critical Care Ultrasound - Blended
The Blended Introduction & Advanced Critical Care Ultrasound Training Course provides participants a strong foundation to perform and/or interpret the core and advanced ultrasound applications in an emergency or critical care setting as outlined in the WINFOCUS and ACEP ultrasound practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading emergency and critical care ... |
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Introduction to Critical Care Ultrasound - Blended
The Blended Introduction Critical Care Ultrasound Training Course provides participants a strong foundation to perform and/or interpret the core ultrasound applications in an emergency or critical care setting as outlined in the WINFOCUS and ACEP ultrasound practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading emergency and critical care medicine ultrasound experts,... |
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Introduction to Emergency Medicine Ultrasound - Blended
The Blended Introduction to Emergency Medicine Ultrasound Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the core and advanced ultrasound applications as outlined in the ACEP, ACGME, and WINFOCUS ultrasound practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced on... |
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Ultrasound Guided Vascular Access - Blended
The Blended Ultrasound Guided Vascular Access Training Course is planned in accordance with the current Agency for Healthcare Research and Quality (AHRQ), ACEP, and WINFOCUS guidelines and provides participants a strong foundation to perform central and peripheral line techniques in an emergency setting. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading emergency medicine ultrasound... |
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Ultrasound Guided Vascular Access and Nerve Blocks in Emergency Medicine Applications
The Blended Ultrasound-Guided Vascular Access & Nerve Blocks for Emergency Medicine Applications Training Course is designed for Emergency Medicine Physicians seeking to integrate ultrasound-guided central and peripheral line vascular access techniques and ultrasound-guided nerve blocks for pain management, or procedural applications. This course is planned in accordance with AHRQ, ACEP, ACGME, and WINFOCUS guidelines. The Blended Education format provides flexibility while saving time and... |
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Advanced Critical Care Ultrasound - Blended
The Blended Advanced Critical Care Ultrasound Training Course provides participants a strong foundation to perform advanced critical care ultrasound applications as outlined in the WINFOCUS and ACEP practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading emergency and critical care medicine ultrasound experts, the online course incorporates comprehensive lectures, cas... |
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Advanced Emergency Medicine Ultrasound - Blended
The Blended Advanced Emergency Medicine Ultrasound Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the advanced ultrasound applications as outlined in the ACEP, ACGME, and WINFOCUS ultrasound practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Tau... |
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Ultrasound Guided Nerve Blocks in Emergency Medicine Applications - Blended
This Blended Ultrasound-Guided Nerve Blocks for Emergency Medicine Applications Training Course is designed for Emergency Medicine Physicians seeking to integrate ultrasound-guided nerve blocks for pain management, or procedural applications into their clinical practice. It is the position of American College of Emergency Physicians (ACEP) that Ultrasound-guided nerve blocks are a core skill which emergency physicians are capable of providing to patients. Ultrasound-guided nerve blocks will so... |
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32nd Annual Primary Care Conference, Session 1
Continuing Education Company has been organizing its Primary Care Conference Series for over 31 years. The Primary Care Conference is designed to update primary care clinicians in rapidly changing therapeutic areas. The emphasis is on practical and useful information for clinical practice. Join us this June or July when we hold the 32nd Annual Primary Care Conference. This conference will be repeated in two sessions for convenience in scheduling. Sessions I and II will be held at the Kiawah Is... |
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Build Your Own Case Study | Obesity: Treating the Whole Patient
Activity Description
Obesity is a chronic, progressive, relapsing disease that impacts health and quality of life. In individuals with obesity, there are many contributors to its development and persistence, including lifestyle, social, and economic factors. If left untreated, obesity can be a primary driver of serious health consequences. By treating obesity first, complications arising from obesity may improve or resolve. Given the severity of the disease, there is a need for clinicians in ... |
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Answering the Call in Severe Asthma Expanding Roles for Biologic Treatment Regimens
This enduring Call-a-Colleague™ educational program will guide attendees through the long-term management of severe asthma. Expert faculty will provide actionable recommendations on evaluation strategies that consider underlying mechanism of disease, data on newer biologic treatment options, and most importantly, the use of these therapies in current day practice. Interspersed throughout the program are brief Call-a-Colleague™ video calls in which faculty consult with their specialist coll... |