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Trauma and Acute Care Sonography - Blended Course
The Trauma and Acute Care Sonography Blended Training Course is specifically designed for physicians, sonographers and other medical professionals who need trauma and acute care sonography training and provides participants a strong foundation to perform the core ultrasound applications as outlined in the ACEP ultrasound practice guidelines.
Begin with the self-paced online course: Taught by leading emergency medicine ultrasound experts, the online course incorporates comprehensive lectur... |
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Advanced Emergency Medicine Ultrasound - Blended Course
The Advanced Emergency Medicine Ultrasound Blended Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the advanced ultrasound applications as outlined in the ACEP, ACGME ultrasound practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leadi... |
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Italy & Dalmatian Coast Cruise - Exploring Medicine, Dentistry & the Mediterranean Healthcare Model
Join PES and sail the sparkling waters of the Adriatic & Mediterranean Seas for 8 nights. Explore the splendors of Croatia, Montenegro, Sicily and the Amalfi Coast aboard the 342-guest flagship yacht Wind Surf, the world’s largest sailing ship!
Exploring Medicine, Dentistry & the Mediterranean Healthcare Model
CME/CE Lecture Seminars for Medical, Dental, Nursing, and Allied Healthcare Professionals
This Seminar is planned for 12 Continuing Education Credit Hours.
CME/CE Pro... |
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Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults
STATEMENT OF NEED
Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w... |
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Current Standards and New Directions in the Treatment of Acquired Thrombotic Thrombocytopenic Purpura
STATEMENT OF NEED
Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy with a rapid onset and progression and a mortality rate of 10% to 20% with prompt treatment. Onset of aTTP is characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and a constellation of associated symptoms including hemorrhage, neurologic and renal manifestations, cardiac abnormalities, and mesenteric ischemia (Joly et al, 2017). Survivors of f... |
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Recurrent and Metastatic HNSCC: New Insights and Real-World Evidence for Improved Patient Outcomes
STATEMENT OF NEED
Head and neck cancers represent a heterogeneous group of tumors that originate in the lip/oral cavity, hypopharynx, oropharynx, nasopharynx, and larynx. An estimated 66,470 new cases are diagnosed in the United States annually, and 15,050 people die of the disease (Siegel et al, 2022). Approximately 90% of cases are classified as head and neck squamous cell carcinoma (HNSCC). Treatment of HNSCC is complicated by numerous factors, including differing therapeutic strategies ... |
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Exploring Novel Treatments for Rett Syndrome
STATEMENT OF NEED
Rett syndrome is a rare, debilitating neurodevelopmental disorder almost always associated with a spontaneous mutation in the methyl-CpG-binding protein 2 (MECP2) gene on the X-chromosome. Affected individuals experience loss of purposeful hand skills, abnormalities in gait, loss of spoken language, and stereotypic hand movements, with more severe manifestations including seizures, autistic features, autonomic nervous system dysfunction, breathing abnormalities, sleep dist... |
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Keeping Up with CAR T-cell Therapy: A Case-based Challenge of CART in NHL + MM
Nurses are often at the front lines of clinical care and as such, are perfectly positioned to bridge the gap between evolving clinical evidence and patient-centered care in Non-Hodgkin’s Lymphoma (NHL) and Multiple Myeloma (MM). This dynamic educational activity will equip nursing professionals with the critical skills to integrate the latest advancements in CAR T-cell therapy into practice, ensuring alignment with NCCN guidelines and patient preferences. Through interactive case studies and... |
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10th Annual Clinical Issues in Primary Care Conference
Embark on an extraordinary Hawaiian adventure from May 12-16, 2025, as Continuing Education Company presents the 10th Annual Clinical Issues in Primary Care Conference at the luxurious Fairmont Orchid Resort. Immerse yourself in a tropical CME conference designed for primary care clinicians eager to ride the wave of the latest therapeutic advancements. Nestled amidst the Big Island's beauty, this medical conference is your passport to engaging sessions, practical insights, and evidence-ba... |
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29th Annual Hypertension, Diabetes & Dyslipidemia Conference
Combine medical education and southern charm at the 29th Annual Hypertension, Diabetes, & Dyslipidemia Conference, happening from June 18-20, 2025, at the Hyatt Regency in Savannah, GA. Immerse yourself in a dynamic CME-accredited program, garnering 15.25 credits, designed to address the complexities of diabetes, hypertension, and dyslipidemia. Join healthcare professionals in the historic setting of Savannah, where centuries-old tradition will meet modern clinical insights, creating a tru... |
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Powder Free Nitrile Gloves Manufacturers in India - Enliva
Enliva offers high-quality Powder Free Nitrile Gloves for healthcare professionals' safety and comfort. Find the best hand safety solutions now! |
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33rd Annual Primary Care Conference, Session 1
Emmerse yourself in the allure of Kiawah Island, South Carolina, while enhancing your medical expertise at the 33rd Annual Primary Care Conference, CEC's oldest and most popular CME conference. Attend one of two sessions: June 23 - 27 or June 30 - July 4 at the prestigious Kiawah Island Golf Resort. This event allows primary care clinicians to stay updated in rapidly changing therapeutic areas with time to explore Kiawah Island's pristine beaches and lush marshlands, where CEC has be... |
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Lifestyle Medicine: Tools for Promoting Healthy Change - LIVE STREAMING
State-of-the-Art Approaches to Help Patients Initiate and Sustain Health-Promoting Behaviors
Lifestyle Medicine will be held online this year, using live streaming, electronic Q&A, and other remote learning technologies.
Overview
This immersive two-day course offers state-of-the-art strategies to guide patients to healthier lives. Education includes evidence-based strategies, tools and techniques to effect healthier changes in patients (and ourselves), including weight loss, exerci... |
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33rd Annual Primary Care Conference, Session 2
Elevate your medical practice at the 33rd Annual Primary Care Conference, CEC's longest-running and most popular CME event, hosted at the prestigious Kiawah Island Golf Resort. Held during two sessions from June 23 - 27 or June 30 - July 4, you have the flexibility to choose the dates that best fit your schedule.
Prepare for enlightening morning sessions led by expert faculty, covering a comprehensive array of topics tailored to the evolving needs of primary care clinicians. Dive into ... |
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Lp(a) and LDL-C Management: Exploring Divergent Perspectives
Target Audience
The intended audience for this activity is cardiologists, endocrinologists, internists, pharmacists, nurses, and other healthcare professionals involved in the management of patients with hyperlipidemia and other cardiovascular risk factors.
Program Overview
Lp(a) and LDL-C Management: Exploring Divergent Perspectives is a continuing education (CE) initiative aimed at broadening healthcare professionals' understanding of the complex nature of hyperlipidemia management... |
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Comprehensive Management of Von Hippel-Lindau Disease: Genetic and Oncological Perspectives
STATEMENT OF NEED
Von Hippel-Lindau disease (VHL) is an autosomal dominant disease in which germline pathogenic variants in the VHL gene predispose individuals to specific types of benign tumors, malignant tumors, and cysts in multiple organs, including clear cell renal cell carcinoma (RCC), renal cysts, central nervous system hemangioblastomas, retinal hemangioblastomas, pancreatic tumors and cysts, endolymphatic sac tumors, and cystadenomas of the epididymis and broad ligament (NIH, 2024). ... |
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Thyroid Eye Disease Mastery: Multidisciplinary Approaches to Diagnosis and Treatment
Thyroid eye disease (TED) is a multifactorial autoimmune disease with widely varied signs and symptoms. It is believed to result from the stimulation of several receptors located in the orbital fibroblasts and is usually associated with hyperthyroidism. However, 5% of patients with TED have hypothyroidism, and 5% have no sign of thyroid disease; thus, it is frequently misdiagnosed. Misdiagnosis can place patients at risk for disfigurement and permanent vision loss, because treatment is most ef... |
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Pediatric RSV Prophylaxis: An Evolving Landscape for Prevention " A Wheel of Knowledge Challenge!
Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis and pneumonia in children younger than 1 year of age in the United States. Although certain infants and young children are at higher risk for severe illness due to premature birth or comorbid conditions, the majority of pediatric RSV hospitalizations occur in healthy infants. Emerging passive immunization options, which include nirsevimab and a maternal RSV vaccine, provide important new tools that offer RSV protection... |
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9th Annual Internal Medicine in Primary Care Conference
Prepare to embark on an extraordinary voyage of discovery and rejuvenation aboard the Celebrity Edge, where the 9th Annual Internal Medicine in Primary Care Conference awaits amidst the awe-inspiring landscapes of Alaska. From July 25 to August 1, 2025, immerse yourself in the natural splendor of the Inside Passage as you sail through pristine fjords, past towering glaciers, and alongside majestic wildlife. This unique cruise offers a perfect blend of educational enrichment and leisurely explo... |
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Beyond Avoidance: IgE-Mediated Food Allergies " Therapeutic Innovations to the Rescue
In the United States, food-induced allergic reactions are the leading cause of anaphylaxis in hospital emergency departments. Among these, immunoglobulin E (IgE)-mediated food allergies are the most common, and they pose significant risks, including cardiac arrest and respiratory failure. Traditionally, treatment options for IgE-mediated food allergies have been primarily limited to food avoidance and anaphylaxis prevention. However, recent years have brought the FDA approval of the first oral... |
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Podcast: Multidisciplinary Task Force and Position Statement: Mitigating Disease Burden and Health Care Disparities in Relapsed/Refractory Multiple Myeloma
STATEMENT OF NEED
With the complex and rapidly evolving treatment landscape of multiple myeloma, it is vital that clinicians not only understand factors for informing selection of current and emerging combination and sequential therapeutic strategies, but also employ interdisciplinary strategies for reducing disparities in relapsed/refractory multiple myeloma care. The development of novel therapeutic options has significantly improved treatment outcomes for patients with relapsed/refractor... |
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Hypertrophic Cardiomyopathy: Unmasking Disparities and Forging a Path to Equitable Care
This comprehensive continuing education (CE) monograph delves into the complexities of HCM, an autosomal dominant genetic disorder marked by increased left ventricular hypertrophy. This condition can lead to significant health complications, such as heart failure, arrhythmias, stroke, and sudden cardiac death. Despite the impact of HCM on patient health and well-being, a gap persists in the understanding of the racial/ethnic and gender-based disparities among healthcare professionals. This gap... |
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Hypertrophic Cardiomyopathy: Unmasking Disparities and Forging a Path to Equitable Care
This comprehensive continuing education (CE) monograph delves into the complexities of HCM, an autosomal dominant genetic disorder marked by increased left ventricular hypertrophy. This condition can lead to significant health complications, such as heart failure, arrhythmias, stroke, and sudden cardiac death. Despite the impact of HCM on patient health and well-being, a gap persists in the understanding of the racial/ethnic and gender-based disparities among healthcare professionals. This gap... |
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Extending Dosing Intervals in Retinal Disease: Patient Perspectives and Clinical Insights to Guide Your Practice
Neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME) are increasingly prevalent retinal diseases that pose significant challenges in ophthalmic care. While anti-vascular endothelial growth factor (VEGF) therapies have greatly improved visual outcomes for patients with these conditions, real-world data indicate that many patients receive suboptimal treatment and monitoring, resulting in poorer visual outcomes. Newer therapeutic options have been developed to exte... |
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Nutraceuticals for Dry Eye: Dispelling the Dogma and Embracing the Data
Dry eye disease is a common yet frequently overlooked condition that significantly affects quality of life. Despite an estimated global prevalence of up to 50%, DED is often underdiagnosed and inadequately managed. To limit the burden of DED, it is crucial for clinicians to be adept at recognizing risk factors and making accurate diagnoses. In addition, as treatment options expand to include clinically proven nutraceuticals, it is imperative that clinicians stay abreast of the latest clinical ... |
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Patient‐Centered GA Care: A Synergistic Approach to Optimize Management
The recent FDA approval of 2 novel therapies for the management of patients with geographic atrophy (GA) secondary to age-related macular degeneration has further reenforced the necessity for early GA diagnosis to limit progression. Advances in imaging technologies now provide tools for better detection and characterization of GA, along with biomarkers to monitor progression over time. Optometrists, as front-line eye healthcare providers, play a critical role in the timely diagnosis, managemen... |
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Advances in Recurrent/Metastatic Nasopharyngeal Carcinoma: Immunotherapy and Biomarkers
Target Audience
This activity was developed for medical oncologists, head and neck surgeons, radiation oncologists, physician associates, nurse practitioners, nurses and pharmacists involved in the care of patients diagnosed with metastatic nasopharyngeal carcinoma (NPC).
Program Overview
Greater understanding of the tumor microenvironment of nasopharyngeal carcinoma (NPC) has led to the introduction of immunotherapy into the NPC treatment landscape. Incorporating immunotherapy has change... |
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Cracking the Code to Successful Stem Cell Mobilization in Multiple Myeloma
STATEMENT OF NEED
Multiple myeloma is the leading indication of autologous hematopoietic stem cell transplantation (ASCT) in hematologic malignancies, with high-dose therapy followed by ASCT representing a potentially curative treatment modality for eligible patients. Collecting peripheral blood stem cells (PBSCs) is an essential component of ASCT, and the collection of sufficient autologous PBSCs relies on the successful mobilization of hematopoietic stem cells from the bone marrow niche i... |
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Prevention of Medical Errors in Nursing Practice
STATEMENT OF NEED
Medical errors are among the most common health-threatening mistakes that affect patient care, accounting for as many as 250,000 deaths per year in the United States (Makary & Daniel, 2016). Medical errors are considered a global problem; they affect as many as 20% of patients in primary and outpatient care and complicate a patient’s primary condition for which they needed medical attention (WHO, 2019). These errors can lead to adverse outcomes, such as increased mor... |
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Halting the Spiral in Worsening Heart Failure: A Virtual Patient Simulation.
Target Audience
The intended audience for this activity includes cardiologists and cardiology advanced practice providers involved in the management of patients with heart failure.
Program Overview
Despite advances in guideline-directed medical therapy, patients with heart failure with reduced ejection fraction (HFrEF) often experience worsening symptoms, leading to increased hospital admissions and a higher risk of adverse outcomes. Halting the Spiral in Worsening Heart Failure: A Virtua... |
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Obesity Forum® FAQs: A Podcast Series
Obesity is an increasingly prevalent, chronic condition associated with substantial risks of morbidity and mortality. It is also a risk factor for some of the leading causes of preventable death, including cardiovascular disease, stroke, type 2 diabetes mellitus, sleep apnea, gallbladder disease, osteoarthritis, and certain types of cancer. The 12th Annual Obesity Forum was a 2-part series that provided health care professionals with guidance on the appropriate use of therapies as well as stra... |
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Pediatric RSV Prevention " Unlocking New Insights
Respiratory syncytial virus (RSV) is a leading cause of bronchiolitis and pneumonia in infants and young children, particularly those under 1 year of age in the United States. While infants born prematurely or with underlying health conditions are at a higher risk for severe RSV illness, the majority of pediatric RSV hospitalizations occur in otherwise healthy infants. Recent advancements in passive immunization, including long-acting monoclonal antibodies and maternal RSV vaccines, introduce ... |
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Pre-Hospital Ultrasound - Blended Course
Pre-hospital ultrasound can be a valuable tool to rapidly diagnose a variety of conditions associated with trauma and/or critically ill patients. Pre-Hospital focused evaluation of the heart, lungs, and abdomen can provide a rapid and safe method to improve the time to diagnose and/or treat these patients resulting in increased patient safety, satisfaction, and over-all improved patient outcomes in time-sensitive situations.
The Pre-Hospital Ultrasound Blended Training Course is specificall... |
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Introduction to Emergency Medicine Ultrasound - Blended Course
The Introduction to Emergency Medicine Ultrasound Blended Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the core and advanced ultrasound applications as outlined in the ACEP and ACGME ultrasound practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online co... |
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POCUS for Family Medicine - Blended Course
The POCUS for Family Medicine Ultrasound Blended Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the core ultrasound applications as outlined in the AAFP/ACEP ultrasound practice guidelines. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading emergency medic... |
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POCUS for Internal Medicine - Blended Course
The POCUS for Internal Medicine Ultrasound Blended Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the core ultrasound applications as outlined in the AAFP and ACEP ultrasound practice guidelines. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading emergency med... |
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Trauma and Acute Care Sonography - Blended Course
The Trauma and Acute Care Sonography Blended Training Course is specifically designed for physicians, sonographers and other medical professionals who need trauma and acute care sonography training and provides participants a strong foundation to perform the core ultrasound applications as outlined in the ACEP ultrasound practice guidelines.
Begin with the self-paced online course: Taught by leading emergency medicine ultrasound experts, the online course incorporates comprehensive lect... |
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Advanced Emergency Medicine Ultrasound - Blended Course
The Advanced Emergency Medicine Ultrasound Blended Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the advanced ultrasound applications as outlined in the ACEP and ACGME ultrasound practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by ... |
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Podcast: Multidisciplinary Task Force: Diagnosis and Management of Dedifferentiated Liposarcoma
STATEMENT OF NEED
Dedifferentiated liposarcoma (DDLPS) is an aggressive subtype of soft tissue sarcoma. Detection of MDM2 and/or CDK4 amplification distinguishes DDLPS from other types of undifferentiated sarcomas. Diagnosis of DDLPS remains challenging due to its complex karyotypes, quantitative genomic profiles, and pleomorphic pathological features (Nishio et al, 2021; Shen et al, 2022). Currently, surgical resection with or without radiation is the mainstay of treatment for localized di... |
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5th International Conference on Cardiology
We are delighted to invite you to the 5th International Conference on Cardiology, from November 28-29, 2025 in Paris, France where ground-breaking discoveries and advancements in cardiac care will take center stage under the theme “Exploring New Horizons in Cardiology and Research”
Heart 2025 conference highlights the new innovative technology in cardiovascular medicine, cardio diseases, paediatric and adolescent cardiology, cardio surgery, cardiac nursing, interventional cardiology, ge... |
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What’s New With HER2: Charting New Paths in NSCLC Care - Module 1: HER2 in NSCLC: Actionable Insights and Testing Recommendations
STATEMENT OF NEED
With the identification of oncogenic drivers and the development of targeted therapies, comprehensive molecular assessment has become a cornerstone of non"small cell lung cancer (NSCLC) management. Human epidermal growth factor receptor 2 (HER2) alterations, which include gene mutations, gene amplifications, and protein overexpression, are emerging therapeutic targets. While testing can be used to guide treatment decisions, the heterogeneity of HER2 alterations and th... |
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What’s New With HER2: Charting New Paths in NSCLC Care - Module 2: Current and Emerging Treatments for HER2-Mutated NSCLC
STATEMENT OF NEED
In recent years, the discovery of oncogenic drivers and development of targeted therapies have transformed the treatment of advanced non"small cell lung cancer (NSCLC). Alterations in human epidermal growth factor receptor 2 (HER2), which include gene mutations, gene amplifications, and protein overexpression, are therapeutic targets. Several HER2-targeted therapies are under investigation in NSCLC and have demonstrated clinical benefit, with trastuzumab deruxtecan re... |
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Podcast: What’s New With HER2: Charting New Paths in NSCLC Care - Module 1: HER2 in NSCLC: Actionable Insights and Testing Recommendations
STATEMENT OF NEED
With the identification of oncogenic drivers and the development of targeted therapies, comprehensive molecular assessment has become a cornerstone of non"small cell lung cancer (NSCLC) management. Human epidermal growth factor receptor 2 (HER2) alterations, which include gene mutations, gene amplifications, and protein overexpression, are emerging therapeutic targets. While testing can be used to guide treatment decisions, the heterogeneity of HER2 alterations and th... |
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Podcast: What’s New With HER2: Charting New Paths in NSCLC Care - Module 2: Current and Emerging Treatments for HER2-Mutated NSCLC
STATEMENT OF NEED
In recent years, the discovery of oncogenic drivers and development of targeted therapies have transformed the treatment of advanced non"small cell lung cancer (NSCLC). Alterations in human epidermal growth factor receptor 2 (HER2), which include gene mutations, gene amplifications, and protein overexpression, are therapeutic targets. Several HER2-targeted therapies are under investigation in NSCLC and have demonstrated clinical benefit, with trastuzumab deruxtecan re... |
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Introduction to Adult Echocardiography - Live Course
The Introduction to Adult Echocardiography Live Training & CME Course is a five (5) day comprehensive echocardiography course in St. Petersburg, FL that is taught by leading echocardiography experts and is designed to provide a strong foundation to perform and/or interpret adult cardiac ultrasound examinations. All topics of discussion are based on ASE, ACEP and AFFP ultrasound practice guidelines.
The structure of the course is a combination of live lectures, scanning demonstrations, i... |
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Evolving Treatment Paradigms in HR+/HER2- Early Breast Cancer: Advancing Equitable Care in Rural and Underserved Communities
Target Audience
This activity is designed specifically for oncologists, advanced practice providers, and other members of the healthcare team who serve patients from rural and underserved communities.
Program Overview
Hormone receptor"positive, human epidermal growth factor receptor 2"negative (HR+/HER2-) breast cancer accounts for up to 70% of all breast cancer cases. In recent years, therapies such as CDK4/6 inhibitors, PARP inhibitors, and novel endocrine therapies have been ... |
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qFriday: Clinical Question Annual Subscription
WHAT IS IT?
qFriday is a 15 minute CPE course sent directly to your email inbox every Friday. Cases are about current clinical topics that have immediate application to your practice.
HOW DOES IT WORK?
1. Check your email every Friday
2. Complete the 15 minute course
3. Get your CPE
WHY qFRIDAY?
The goal is to be continually learning, striving to stay at the top of our game. qFriday makes learning a habit while giving you 13 hours of Drug Therapy CPE for the year. Use it to stay sh... |
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Brain Trust 2.0: Creating and Managing a Dementia Friendly Primary Care Clinic
Learning Objectives:
Develop key elements of plan of care that meets primary care principles of care access, continuity, coordination, and comprehensiveness.
Deliver trustworthy relationship building that is culturally and contextually tailored.
Name at lest one community resource available to support the person living with ADRD, their caregivers, and the primary care physician
CME Credit Claim: https://form.jotform.com/sortega801/TBT20OnlineCreditClaim
Please complete the posttest, e... |
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Emerging Developments in Human Milk Fortification: Problem Solving for Clinical Practice
Human milk science is evolving at a rapid pace, shaping neonatal nutrition practices significantly. Nonetheless, optimizing growth and development in the NICU remains a challenge. Ariel Salas, MD, MSPH, and Brian Stansfield, MD, are leaders in human milk research, as well as in the clinical application of these findings. In a solutions-based presentation, Drs. Salas and Stansfield present recent clinical trial and real-world data on strategies for optimizing preterm nutrition. In this symposiu... |
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Therapy Tidbits – November/December 2016
Therapy Tidbits – November/December 2016 is a 1-hour online continuing education (CE) course comprised of select articles from the November/December 2016 issue of The National Psychologist, a private, independent bi-monthly newspaper intended to keep mental health professionals informed about practice issues. The articles included in this course are:
New ACA Rule May be Onerous Burden – or Totally Irrelevant – for Psychologists: Gordon Herz, PhD, a clinical psychologist in Madison, WI... |