Tryptase Testing in Chronic Mast Cell Disorders and Acute Settings

Are you familiar with the role of serum tryptase testing in diagnosing idiopathic anaphylaxis and mastocytosis? What role does serum tryptase play in the ongoing management of patients who have anaphylactic reactions to insect venom, and are there different considerations when a patient has a known trigger? Expert faculty Dr. Phil Lieberman shares his insights on serum tryptase testing in clinical practice and its importance in assessing mast cell disorders and anaphylaxis. This moderated discussion is enhanced with animation, key takeaways, and support slides to provide an engaging learning experience.

Serum tryptase plays an important diagnostic role in the setting of mast cell activation resulting from a variety of causes, including mastocytosis and anaphylaxis. Emergency medicine specialists, allergists, and primary care providers serve as the first-line responders to patients experiencing the effects of mast cell activation. The measurement of tryptase levels helps confirm diagnoses and inform management decisions for these life-threatening disorders. To help physicians provide optimal evaluation and management, it is essential that they be knowledgeable regarding the appropriate use of tryptase testing in these clinical settings. This education enables multidisciplinary clinicians to identify patients at risk of mast cell activation due to a variety of causes and employ appropriate use of tryptase testing across acute and follow-up care settings.