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Warm Autoimmune Hemolytic Anemia (wAIHA)
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing people with wAIHA are largely based on case series and retrospective studies involving off-label medications. Also, while there are currently no medications specifically approved to treat wAIHA, data are emerging on new... |
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Expert Guidance on Current Standards and New Directions in Newly Diagnosed Multiple Myeloma
STATEMENT OF NEED
An estimated 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Characterized by clonal proliferation of malignant plasma cells in the bone marrow, multiple myeloma is associated with anemia, renal insufficiency, bone destruction, and hypercalcemia, all of which significantly impact patients’ quality of life. The development of novel therapies and combinations in recent years, inclu... |
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Putting the Freeze on Cold Agglutinin Disease
STATEMENT OF NEED
Cold agglutinin disease (CAD) is a rare subtype of autoimmune hemolytic anemia (AIHA) in which antibodies cause hemolysis at cold temperatures, generally between 37º to 39º Fahrenheit. Approximately 1 in a million people are affected by CAD annually, with onset usually occurring between the ages of 40 and 80 years. Individuals commonly experience fatigue, dizziness, palpitations, and shortness of breath caused by the anemia; jaundice caused by degradation of hemoglobin i... |
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Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults
STATEMENT OF NEED
Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w... |
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Current Standards and New Directions in the Treatment of Acquired Thrombotic Thrombocytopenic Purpura
STATEMENT OF NEED
Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy with a rapid onset and progression and a mortality rate of 10% to 20% with prompt treatment. Onset of aTTP is characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and a constellation of associated symptoms including hemorrhage, neurologic and renal manifestations, cardiac abnormalities, and mesenteric ischemia (Joly et al, 2017). Survivors of f... |
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Operation Game- A Patient’s Journey Through HeFH: Diagnosis and Management
Target Audience
This activity has been designed to address the educational needs of cardiologists, cardiology nurses, lipid specialists, and primary care clinicians, including internists, pharmacists, nurses, nurse practitioners, PAs, and dietitians. It may also benefit other healthcare providers who manage patients with hypercholesterolemia.
Program Overview
Nonstatins are an essential therapy for lowering low-density lipoprotein cholesterol (LDL-C) levels in high-risk patients, such as ... |
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Real-World Perspectives in Managing CLL Treatment
Management options for chronic lymphocytic leukemia (CLL) have expanded in recent years. The emergence of new immunotherapeutic and targeted agents for both the first-line and relapsed/refractory settings"though of course beneficial for CLL patients"represents a challenge to clinicians, who must navigate the indicated uses, mechanisms of action, and toxicity profiles of these new agents. In determining optimal treatment plans, clinicians are also confronted with significant advances ... |
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Diabetes Update 2024 - LIVE STREAMING
This highly rated Harvard Medical School CME course offers practical strategies to address the medical and systemic challenges to optimal care and updates that ensure you can deliver state-of-the-art care for your patients with diabetes.
PROGRAM HIGHLIGHTS
This program affords you the opportunity to learn from leaders in the field of diabetes who are distinguished for their outstanding teaching, knowledge, and innovations in clinical care.
Participants can rely on this program for compreh... |
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Warm Autoimmune Hemolytic Anemia (wAIHA)
Target Audience
This activity has been designed to meet the educational needs of physicians specializing in hematology and hematology-oncology. Other members of the care team may also participate.
Program Overview
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing ... |
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In Case You Missed: Utilizing the Muscarinic System to Optimize Treatment Options for Schizophrenia
Schizophrenia is an incurable, neuropsychiatric disease characterized by difficulties thinking and communicating clearly as well as psychosis (ie, “positive” symptoms); difficulty functioning socially (ie, “negative” symptoms); and cognitive impairment. As many as 34% of patients with schizophrenia have treatment-resistant schizophrenia, defined as continuing symptoms despite at least 2 trials of appropriate antipsychotic treatment, and most people do not recover from it. Patients with... |
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28th Annual Hypertension, Diabetes & Dyslipidemia Conference
This three day intensive conference, held on June 19-21, 2024 in Charleston, South Carolina, addresses all the issues confronting clinicians who treat challenging patients with diabetes, hypertension, and dyslipidemia and how to apply this knowledge to everyday practice.
Over the past several years controversies in the appropriate target for Hemoglobin A1C, BP, and LDL-Cholesterol on outcome improvement continue to occur in Type 2 diabetes, Hypertension, and Dyslipidemia, respectively. Desp... |
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How I Treat Paroxysmal Nocturnal Hemoglobinuria (PNH)
In this point-counterpoint digital activity, two expert faculty discuss and debate treatment selection for patients with PNH through case-based scenarios. Faculty review mechanisms of action, clinical trial data, and real-world evidence supporting divergent treatment strategies for the presented cases. How do the experts make their initial treatment selections? Why might they choose a C5 inhibitor or a C3 inhibitor? How do they assess response to treatment, and what do they do when treatment r... |
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Internal Medicine Comprehensive Review and Update 2024 - LIVE STREAMING
Comprehensive, Evidence-Based Updates for Internal Medicine and Its Subspecialties
This program, the 64th annual Internal Medicine Update from the leading clinical faculty of Harvard Medical School and Massachusetts General Hospital, provides comprehensive, high-yield instruction to ensure clinicians are current with the latest evidence and best practices to optimize patient care.
This program covers the breadth of Internal Medicine subspecialties, including:
• Cardiovascular Medicine
... |
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Diabetes Comorbidities and Complications - LIVE STREAMING
This comprehensive course, which is among the highest-rated Harvard Medical School CME courses, provides education and updates to optimize your care of patients with diabetes and these conditions:
• Obesity
• Cardiovascular Disease
• Heart Failure
• Coronary Artery Disease
• Cerebrovascular Disease
• Hypertension
• Hyperglycemia
• Hypoglycemia
• Dyslipidemia
• Metabolic-Associated Fatty Liver Disease
• Chronic Kidney Disease
Sessions are led by experts in thes... |
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Best of ACTHIV® 2023: Hepatitis B in People with HIV
Selected by attendees and the program planning committee as one of the best sessions of the ACTHIV® 2023 conference for the frontline HIV care team, this module will examine best practices for evaluating people with HBV and HIV and will review the risk of liver complications associated with HBV viremia in people with HIV.
Describe best practices for evaluating people with HBV and HIV
Appraise the risk of liver complications associated with HBV viremia in people with HIV |
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Applying Evolving Targeted Therapy in Acute Myeloid Leukemia
Acute Myeloid Leukemia (AML) is a biologically heterogeneous hematologic malignant neoplasm with a 5-year survival rate of 30%. Hematologist, Brian Jonas, MD, PhD, UC Davis Comprehensive Cancer, discusses standard induction, consolidation, and maintenance therapy, as well as factors to consider in individualizing intensive therapy in fit and unfit patients. Dr. Jonas presents safety and efficacy data for approved and emerging therapies that target BCL-2, FLT-3 ITD/TDK, CD33, CD47, IDH1/2, E-se... |
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Nursing Management of Tumor Lysis Syndrome
STATEMENT OF NEED
Tumor lysis syndrome (TLS) is an oncological emergency that occurs when massive tumor lysis causes the rapid release of intracellular components into the bloodstream. Electrolyte imbalances characterized by hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia may be severe enough to cause acute renal failure, cardiac arrhythmias, seizures, and even death. Current advances in cancer therapies can increase the incidence of TLS; therefore, identification of patien... |
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Therapeutic Advancements for the Treatment of High-Risk MDS: Future Opportunities to Improve Patient Survival and Quality of Life
Stay up to date on the evolving risk classification for myelodysplastic syndromes (MDS) and current treatment guidelines for patients with high-risk disease in this self-directed education with leading oncology experts. Expert commentary from Courtney DiNardo, MD from MD Anderson Cancer Center and Dr. Dan Pollyea from the University of Colorado School of Medicine provides insights on emerging therapies that could soon improve management of high-risk MDS. Be ready to incorporate these emerging ... |
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Update in Clinical Cardiology - LIVE STREAMING or IN PERSON
The Comprehensive Clinical Cardiology Update
Evaluation • Treatment • Patient Care • Procedures • Challenging Cases
Update in Clinical Cardiology will be held on October 16 " 18, 2024. You have the option to attend either online as the course is live streamed or in person in Boston, MA.
OVERVIEW
This course provides comprehensive updates for state-of-the-art care and guidance to incorporate them into daily practice to optimize patient outcomes.
Coverage includes:
• ... |
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The Critical Role of Managed Care Pharmacists in Optimizing Treatment of Iron Deficiency in Patients with Heart Failure
Despite evidence-based interventions to prevent or manage heart failure (HF), poor HF-related outcomes persist as evidenced by the number of preventable HF-related hospitalizations and high readmission rates. Moreover, the economic burden that HF places on the health care system is significant. Pharmacists can improve adherence to guideline recommendations for the use of intravenous (IV) iron therapy for patients with HF and iron deficiency (ID) and develop treatment pathways and implement for... |
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Understanding Cholesterol Guidelines and Implementing Non-statins in High-Risk Populations: Paired Conversations and Case Vignettes
An interprofessional faculty of primary care and specialty clinicians discuss real-world issues in managing patients with complex and challenging dyslipidemia, including elevated lipoprotein a (Lp(a)). Several paired conversations serve as the foundation for discussions related to recent cholesterol guidelines, patient risk stratification, and recommended goals for patients at risk of atherosclerotic cardiovascular disease. Two case vignettes provide the basis for robust discussion among the f... |
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Improving Selection and Utilization of Continuous Glucose Monitors (CGM) for People with Diabetes
Self-monitoring of blood glucose (BG) levels is critical to daily self-management for people with diabetes. Studies have shown that intensive insulin regimens and BG control corresponded with better glycemic control have resulted in a significant decrease in the microvascular complications of diabetes. Because CGM is still an evolving technology, both clinicians and patients would benefit from engaging, interactive, and evidence-based education to improve the utilization of these tools. |
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Conquering Lab Interpretation (eLearning)
No matter what your area of expertise, no field in medicine spends enough time training you for lab interpretation. Join us as we conquer the interpretation of lab findings to help you gain the clues you need to provide better care to your patients. What we understand, we can then use to set up the plan of the day, to progress the patient towards good outcomes and to predict the next step in the treatment goal. Data collection and understanding are important steps in the development of critica... |
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Conquering Lab Interpretation (DVD-ROM)
No matter what your area of expertise, no field in medicine spends enough time training you for lab interpretation. Join us as we conquer the interpretation of lab findings to help you gain the clues you need to provide better care to your patients. What we understand, we can then use to set up the plan of the day, to progress the patient towards good outcomes and to predict the next step in the treatment goal. Data collection and understanding are important steps in the development of critica... |
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The latest insights into rare blood disorders: Diagnosis and treatment strategies
Because immune-mediated rare blood disorders are uncommon, healthcare providers often lack the knowledge and experience necessary to identify, diagnose, and treat them in accordance with best practices. As a result, there are significant gaps in care, including delays in diagnosis and suboptimal treatment. To ensure that more patients with these rare disorders are offered quality, evidence-based care, it is essential that healthcare providers possess up-to-date information about best practices... |
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Unmasking Multiple Myeloma and Its Precursor Conditions in Primary Care
For multiple myeloma (MM) patients to receive the most appropriate care, a quick and accurate diagnosis is paramount. This is especially the case for Black patients, as diagnosis has historically been slower in Black patients"even though MM is twice as common in Black Americans than in White Americans. Additionally, MM precursor conditions such as monoclonal gammopathy of undetermined significance are seen more frequently in Black Americans than in White Americans. Primary care providers ... |
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Long-Chain Fatty Acid Oxidation Disorders: Advances in Nutritional Management
Target Audience
This activity is designed to meet the educational needs of Registered Dietitians.
Program Overview
Long-chain fatty acid oxidation disorders (LC-FAODs) are characterized by acute crises of energy production and chronic energy deficiency during times of physiologic stress and fasting. Clinical complications include recurrent episodes of rhabdomyolysis, weakness, hepatic dysfunction, severe hypoglycemia, hyperammonemia, and cardiomyopathy. Despite a traditional diet therapy,... |
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Cleveland Clinic 27th Annual Diabetes Therapeutics, Technology and Surgery (Online Streaming On Demand)
For over a quarter century, Cleveland Clinic has been at the forefront of continuing education regarding the treatment and management of diabetes. Its world class faculty has designed the 27th Annual Diabetes Therapeutics, Technology and Surgery to provide up-to-date reviews of strategies and research relevant to this disease and its complications. The goal of this activity is to increase practitioners’ competence and clinical performance in the management of type 1 and type 2 diabetes. A... |
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Cleveland Clinic Primary Care + (online streaming & flash drive formats)
Cleveland Clinic Primary Care + highlights the latest therapies, procedures and diagnostics in primary care, women’s health and behavioral medicine. This best practices review addresses the educational needs of primary care clinicians who must stay abreast of current research and treatments in a wide range of disciplines. Physicians, nurses and physician assistants will all benefit from Cleveland Clinic’s expert analysis of essential subjects in primary care.
Worth 21 AMA PRA Catego... |
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Advances in™ Beta-Thalassemia: The Evolving Therapeutic Landscape
Target Audience
This educational activity is directed toward hematologists and hematologist-oncologists, as well as pediatricians, nurses, nurse practitioners, physician assistants, and other clinicians involved in the management of patients with beta-thalassemia.
Program Overview
This online educational activity is designed to provide expert interpretation of new and emerging data on the treatment of β-thalassemia, with a forward-looking perspective on how new and novel agents might imp... |
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Therapy Tidbits Fall 2020
Therapy Tidbits – Fall 2020 is a 1-hour online continuing education (CE) course comprised of select articles from the Winter 2020 issue of The National Psychologist, a private, independent, quarterly newspaper intended to keep psychologists informed about practice issues. The articles included in this course are:
Stress for Psychologists Piles up During Pandemic – Highlights the ways in which the pandemic has affected psychologists and stresses the importance of caring for oneself.
Sex... |
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