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Learning Objectives Upon completion of this activity, participants should be able to: 1. Define drug allergy in relation to adverse drug reactions. 2. Discuss the incidence and risk factors of drug allergies in the general population. 3. Evaluate cross-reactivity between agents to provide alternative recommendations to patients. 4. Describe common drug allergies and the appropriate treatment options. 5. Explain the role of the pharmacist in the management of drug allergies.

Medication errors in hospital settings have been associated with high rates of adverse drug reactions and even death. Technological advances, such as barcode scanners, can help prevent medication errors, having been shown to reduce the medication error rate in an ICU setting by 56%. This educational program will review the root problem of medication errors and the potential impact of barcode scanning in improving patient outcomes. **Upon completion of this activity, nurses and pharmacists w...

Objectives 1. Review major categories of respiratory medications, summarizing mechanisms of action and clinically significant adverse effects. 2. Delineate select toxicities associated within each class of respiratory medication. 3. Highlight select drug interactions associated with each class of respiratory medications. 4. Recognize trends of abuse and related adverse effects for certain respiratory medications, such as dextromethorphan and clenbuterol. 5. Review the pot...

This course will provide participants with an understanding of drug safety at the investigational stage and during the marketing phase. Adverse event identification and reporting requirements will be addressed, as well as FDA, EMEA, Health Canada and ICH roles in the drug safety process. The course will also discuss international law/regulations, ICH guidelines, Pharmacovigilance, definitions and current regulatory issues. Adverse event reporting requirements specific to the US, Canada, Japan...

Food allergy affects nearly 4% to 5% of children and approximately 3% to 4% of adults in the United States, and the prevalence has been increasing since 1997. The number of deaths associated with food allergy remains relatively low, but some reactions can be life-threatening, making it necessary to ensure that individuals with food allergy and their families understand the potential severity of the allergy. This course provides an overview of food allergy, beginning with a definition of food a...

Learning Objectives 1. Describe the mechanism of action of tapentadol immediate release (IR). 2. Determine the appropriate dose and dosing schedule for tapentadol IR. 3. Recognize tapentadol IR's contraindications, warnings and precautions. 4. Identify adverse effects that have been associated with tapentadol IR. 5. Discuss potential drug-drug interactions with tapentadol IR.

1. Present an overview of gout and its standard therapy. 2. Highlight febuxostat pivotal trials. 3. Identify febuxostat potential adverse effects and the ramifications in patient's care. 4. Define the place of febuxostat in the treatment of gout.

Upon completion of this activity, you will be able to: * identify indications for emergency-release RBC transfusion. * identify the risks of emergency-release RBC transfusion. * recognize and diagnose hemolytic transfusion reactions.

Objectives 1. Describe the epidemiology and risk factors for drug-induced lung disease. 2. Review the common patterns of drug-induced lung injury. 3. Review the diagnostic evaluation of patients with suspected drug-induced lung disease. 4. Understand the principles of management of drug-induced lung disease. 5. Describe features of drug-induced lung disease due to novel biological agents.

Learning Objectives: Upon successful completion of this program, pharmacists should be able to: 1. Identify factors that contribute to the high prevalence of warfarin drug interactions. 2. Describe the typical time course for warfarin drug interactions. 3. Describe mechanisms for warfarin drug interactions. 4. Discuss various types of drugs or drug classes that are known to interact with warfarin. 5. Discuss strategies to manage warfarin drug interactions and minimize risks.

1. Differentiate the multiple definitions of polypharmacy in order to be able to recognize it in your patient population. 2. Discuss the current data available in evaluating polypharmacy specifically in older adults with cancer and incorporate the data in your evaluation of older patients. 3. Summarize the agents or drug classes that may be deemed inappropriate in older adults to avoid prescribing medications for older patients that may lead to adverse drug events.

Francis E. Marchlinski is a professor of medicine at the University of Pennsylvania and director of electrophysiology at the University of Pennsylvania Health System. He has written and lectured extensively on cardiac arrhythmias. Here, he discusses pharmacologic rhythm control in atrial fibrillation, strategies for anticoagulation in atrial fibrillation, pacing therapy in atrial fibrillation, and device and ablative therapy in cardiac arrhythmias. This lecture and the post-test is worth 2....

**After completion of this course the participant should be able to:** * List seven signs and symptoms of a latex reaction. * Describe factors contributing to the emotional impact a latex allergy has on the patient and family. * List four common household items that contain latex. * Discuss safety measures latex sensitive patients should use * Teach patients when to call the doctor regarding latex reactions and about medications used to treat these reactions. * List the 3 most common cro...

You chose to work in health care in order to care for people. So when you accidentally harm a patient, it can be exceptionally hard to talk about it. In this course, you’ll learn why communicating with patients after adverse events can feel so difficult for health care professionals – and why it’s nonetheless essential. You’ll learn what to say to a patient, and how to say it, immediately after such an event occurs. You’ll also learn how to construct an effective apology that can hel...

The drugs methylenedioxymethamphetamine (MDMA), ketamine, flunitrazepam, and gamma-hydroxybutyrate (GHB), collectively known as "club drugs," have become widely used by college students and by a segment of the youth population that attends all-night dance parties known as "raves." This course will provide the most pertinent up-to-date information regarding the demographics and characteristics of club drug users, pharmacokinetics and pharmacodynamics, clinical signs and symptoms, and available ...

After completing this CME module, participants will be able to 1. Summarize the purpose of the Safe Medical Devices Act of 1990. 2. Define what is meant by an "adverse event" according to the Safe Medical Devices Act. 3. Identify when an adverse event should be reported under the Safe Medical Devices Act, how such events should be reported, and who is required to report. 4. Discuss case examples of adverse event reporting.

Postoperative inflammation can lead to serious adverse outcomes. A thorough understanding of the pathophysiology of inflammation is essential in order to develop effective therapeutic strategies that will prevent the long-term ocular sequelae. Clinicians should be aware of the overall efficacy and safety of available topical anti-inflammatory agents as well as differences in drug potency and drug delivery mechanisms. A panel of expert eye surgeons discusses loteprednol etabonate ointment, a re...

Course Objectives At the completion of this case, the learner will be able to: 1. Assess an older patient for the presence of falls risk factors. 2. Examine a patient’s medication regimen to identify medications known to increase the risk of falling. 3. Interpret a review of systems for the purpose of identifying possible adverse drug events. 4. Recommend a treatment plan to reduce a patient’s falls risk. 5. Specify parameters for monitoring a patient’s drug therapy and outcomes.

In order to prevent overuse and abuse, clinicians, especially pharmacists, must be diligent about monitoring adverse events and potential misuse in their pain patients. Prescription drug abuse is increasing worldwide and Dr. McPherson provides pharmacists with an excellent review of what tools are available to improve assessment and monitoring of pain and drug-related aberrant behaviors. Treatment success can be improved when pain characteristics are properly assessed, and risk of abuse, misu...

Every hospital that received Medicare and Medicaid reimbursement should be aware that CMS amended several important sections to the hospital conditions of participation (CoP) manual including clarifications to the section on nursing requirements related to blood transfusions, IVs, and intravenous medication.Training requirements for nurses and other personnel who administer blood transfusions and intravenous medications will be discussed. Also reviewed will be the changes relating to immediat...

Janet M. Beausoleil, MD, is an assistant professor of pediatrics at the University of Pennsylvania School of Medicine and attending physician at the Children's Hospital of Philadelphia. Here, she provides a definition of anaphylaxis, its mechanisms, and differential diagnosis, and describes its connection to food allergies. Dr. Beausoleil wishes to disclosure that she has appeared as a speaker for GlaxoSmithKline and Merck. Dr. McGintee has no relationships with commercial interests related...

Patients, and in some cases healthcare providers as well, are not fully aware of the health risks incurred by ingestion of herbal medications, either due to their potential adverse effects or pharmacological interactions with other medications. This situation is further compounded by the fact that at least 60% of the patients taking herbal medications do not disclose this fact to their healthcare provider. This course provides the knowledge and tools required for clinicians to discuss natural ...

This course provides an understanding of the interrelated activities throughout the drug development cycle, and is designed for anyone interested in learning how drugs are developed, manufactured and subsequently brought to market. This course serves as an introduction to the drug development process and will familiarize participants with the steps involved in developing a drug from discovery to commercialization. Included is an overview of the regulatory and pre-marketing steps that occur to ...

At the completion of this activity, the participant will be able to: Describe the role of the cytochrome P450 system in metabolic drug interactions. Describe general approaches for the avoidance of patient harm resulting from drug interactions. Describe how to evaluate a drug interaction alert from a computerized screening system.

A renowned ophthalmic surgeon highlights the rationale for the appropriate off-label use of ophthalmic medications and explores the adverse impact of government ‘off-label’ policies as it relates to the traditional practice of dispensing professional drug samples.

This two-day course is designed for those who manage, audit, or oversee manufacturing of OTC drug products, and for cosmetic manufacturers with OTC drug products (no dosage) performing their operation under a drug cGMP environment. The course will cover regulatory expectations as contained in U.S. and International guidelines. It will prepare attendees to assess their current compliance status, develop strategies and plans for remediation of identified gaps, and execute a plan to achieve comp...

ADVANCES IN HIV THERAPY 1. Review and identify the mechansims of HIV infection and targets for pharmacotherapy. 2. Compare and contrast mechanisms of action of various antiretroviral agents. 3. Identify both clinical and laboratory values advocating the initiation of antiretroviral therapy. 4. Identify new agents in the fight against HIV and how they fit into the currently available agents. 5. Understand the antiviral effects associated with high active antiretroviral therapy (HAART)....

Discussing adverse medical events with patient and family is perhaps the most difficult conversation physicians will undertake. Too often, physicians postpone, delegate or avoid these difficult conversations. Prompt, empathic communication initiated by the physician is the best way to safeguard the doctor-patient relationship and reduce the risk of malpractice claims. However, there are many barriers to doing so. This mixed-media Internet/Enduring material will present risk management recomm...

Update on Drug Shortages webinar Presented by Erin Fox,PharmD, Manager, Drug Information Services University of Utah 6:00 to 7:30 pm 1.5 Contact Hours Registration is open until 3:00 pm on Wednesday, June 6, 2012. Late registrants will only be permitted if time and space is available. All participants attending the webinar on June 6 will receive live CE credit. The recorded webinar is home study credit Refund requests must be made prior to June 6. All requests must be in writing by ma...

Study the list of requirements for successful venipuncture. Everything you need to know about venipuncture and pharmacology for contrast media procedures. The techniques for administration, pharmacology of dose units, documentation and charting, and the response to allergic reactions when performing a venipuncture are covered. This is a good study guide.