Leslie Raffini, MD, is an assistant professor of pediatrics in the Division of hematology at Children's Hospital of Philadelphia. She is currently completing a National Hemophilia-sponsored fellowship in clinical hemostasis and thrombosis. She has completed a two-year National Hemophilia Foundation sponsored fellowship in clinical hemostasis. Here, she discusses the epidemiology, risk factors, diagnosis, and therapy of venous thromboembolic events in pediatric patients. The author has no re...

The most common presentations of venous thromboembolism (VTE) are deep vein thrombosis (DVT) of the lower extremity and pulmonary embolism. A risk factor for VTE, either hereditary or acquired, can now be identified in approximately 80 percent of patients. Furthermore, there is often more than one factor at play in a given patient. As an example, 50 percent of thrombotic events in patients with inherited thrombophilia are associated with an acquired risk factor (eg, surgery, pregnancy, oral co...

Atrial fibrillation (AF) is a common heart arrhythmia and the leading cause of cardioembolic events such as stroke, the third leading cause of death in the United States. Survivors of a stroke are at increased risk of subsequent stroke. Therefore, reducing the risk of an initial or recurrent stroke is critical. As the largest single provider of health care in the United States, the Department of Veterans Affairs (VA) is working to improve and standardize the care of patients at risk of stroke....

Upon completion of this activity, you will be able to: * list the types of thrombi most commonly associated with JAK2 mutations. * outline the best test methods to detect JAK2 mutations. * define the risk for and types of myelodysplastic syndromes that may be associated with JAK2 mutations.

Acute pulmonary embolism (PE) encompasses a spectrum of disorders with distinct pathophysiological mechanisms and therapeutic implications. Patients with acute PE who present with normal systemic arterial pressures and no evidence of right ventricular dysfunction have an excellent prognosis when treated with standard anticoagulation alone. Normotensive patients with acute PE and evidence of right ventricular dysfunction are categorized as having submassive PE and comprise a population at incre...

Session 1 – Wednesday, August 8, 2012 - An Evidence-Based Heart Failure Review Session 2 – Thursday, August 9, 2012 - A Comprehensive, Evidence-Based Review of Anticoagulation Session 3 – Friday, August 10, 2012 - A Comprehensive, Evidenced-Based Review of Treating Pain and Suffering

This certified CME/CE activity is designed to heighten the awareness of and adherence to evidence-based guideline recommendations for the prevention of stroke in patients with AF. Co-sponsored by Duke University School of Medicine and Med-IQ, in collaboration with Joint Commission Resources.

This continuing pharmacy education opportunity is unique because it is intended to provide a longitudinal approach to anticoagulation education for the management of Stroke Prevention in Atrial Fibrillation. Participants will be able to obtain knowledge-based continuing education from three on demand Webinars, apply their skills through online case studies, review and discuss controversies with anticoagulation therapy in a six hour on demand symposium, and enhance your practice using a practic...

Target Audience: - Medical directors, pharmacy directors, clinical pharmacists, quality directors, and network physicians affiliated with managed care organizations - Case managers, policy administrators, utilization managers, IT professionals, nurses, and other managed care health professionals Purpose Statement: Managed care pharmacists and affiliated clinicians involved in the care for patients at risk for thromboembolic disorders are routinely challenged with multiple sets of a...

After reading this article, the physician should be able to: * Understand the indications for reversal of warfarin. * Identify the side effects of protamine in heparin reversal. * Recognize the advantages and disadvantages of fresh frozen plasma (FFP) vs. prothrombin complex concentrates (PCC) in the treatment of warfarin reversal.

Objectives 1. Review the definition of acute kidney injury and the RIFLE classification. 2. Determine the indications for renal replacement therapy (RRT) in the ICU. 3. Understand the basic differences between hemodialysis and hemofiltration. 4. Review the current knowledge concerning RRT modalities, dose, timing, and anticoagulation strategies. 5. Describe the impact of RRT on prescribing practices in the ICU. 6. List the complications of RRT.

This certified CME/CE series is designed to heighten the awareness of and adherence to evidence-based guideline recommendations for the prevention of stroke in patients with AF. This series reviews prevalent risk factors for stroke, the importance of aggressive, preventive management, and the application of risk assessment tools to guide therapeutic decision making. The benefits and barriers related to the effective use of antithrombotic therapy in patients with AF and the potential role of em...

Description According to National Institutes of Health, most heart attacks are caused by a blood clot that blocks one of the coronary arteries. The coronary arteries bring blood and oxygen to the heart. If the blood flow is blocked, the heart starves for oxygen and heart cells die. Objectives Upon completion of this educational acitivity the participant will be able to: 1.) Review the pathophysiology responsible for ACS. 2.)Reveiw the current ACC/AHA guidelines for the management of patie...

Upon completion of this activity, you will be able to: * describe the underlying principle of thromboelastography as a test of hemostasis as well as some of its major limitations. * list the individual components of the International Society on Thrombosis and Haemostasis scoring algorithm for overt disseminated intravascular coagulation. * recognize the concept of a consolidated score derived from the various data obtained from the thromboelastogram to assess a hypocoagulable state h...

Track 1: Recommendations for Medical and Pharmacy Directors Track 2: Recommendations for Care Managers Target Audience This activity has been designed to meet the educational needs of medical directors, pharmacy directors, clinical pharmacists, quality directors, registered nurses, as well as network physicians affiliated with various managed care organizations. Statement of Need/Program Overview Managed care professionals and affiliated clinicians involved in the management of an...

Statement of Need Wide use of oral anticoagulants has led to an increasing frequency of warfarin-related bleeding emergencies such as intracranial hemorrhage and excessive bleeding among patients experiencing trauma. Reversal of the coagulopathy associated with bleeding frequently encountered in the emergency department is a clinical problem that remains so because of disagreement and debate about the best strategy for managing these bleeding episodes. Although new and emerging altern...

Primary care physicians manage many of the patients on long term anticoagulant therapy. They perform a difficult balancing act on a daily basis, weighing each patient’s risk of thromboembolism versus hemorrhage. The preponderance of current medical literature identifies under-utilization of anticoagulants as a major problem, and cites the burden of frequent blood work and fear of bleeding as the reason for under-utilization. The Joint Commission has made reducing the risk of patient injuries...

Atrial fibrillation (AF) is the most common form of arrhythmia observed in clinical practice. Although not typically life-threatening itself, AF represents a major risk factor for stroke and major cause of death and serious long-term disability. Approximately 15% of the 795,000 new or recurrent strokes that occur each year develop in patients with AF. Appropriate management of patients with AF involves the assessment of stroke risk and, when indicated, long-term anticoagulation therapy.

This conference will bring together the world leaders in hip and knee joint preservation and reconstruction for a combination of didactic presentations, focused discussions, and surgical demonstrations. Topics discussed will include new surgical approaches, techniques, prostheses, and computer-assisted surgery/robotics. General topics will include infection, deep vein thrombosis, pain management, rehabilitation, and biologicals. Cost analysis and the economics of total knee and hip arthroplast...

Francis E. Marchlinski is a professor of medicine at the University of Pennsylvania and director of electrophysiology at the University of Pennsylvania Health System. He has written and lectured extensively on cardiac arrhythmias. Here, he discusses pharmacologic rhythm control in atrial fibrillation, strategies for anticoagulation in atrial fibrillation, pacing therapy in atrial fibrillation, and device and ablative therapy in cardiac arrhythmias. This lecture and the post-test is worth 2....

New! Prepare for your boards with Gulfcoast's ULTRA "Preparation Agenda for Study Success" tools! Consistent with newly revised ARDMS outlines, the new ULTRA P.A.S.S. Vascular Technology workbook covers all of the material pertinent to the Vascular Technology board exam. Similar to a review book on audio, the ULTRA P.A.S.S. workbook provides comprehensive written and narrated formats (audio CDs, see below). This workbook is designed so you can easily find a specific subject of study at any ...

ATTENTION: SDMS CME credits have expired for this product. Prepare for your boards with Gulfcoast's "Preparation Agenda for Study Success" tools! The P.A.S.S. Registry Review CD Quiz Series is an excellent self-assessment tool for the medical professional preparing to take an ultrasound registry examination or for the educator who has a desire to enhance the current registry review curriculum. The questions posed in each of the P.A.S.S. interactive CD exams are based on current registry ...