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Leveraging BCMA-Directed Therapies for Improved Patient Outcomes in Relapsed/Refractory Multiple Myeloma
STATEMENT OF NEED
Multiple myeloma is a disease that remains incurable for most patients, many of whom become refractory to the majority of available treatments (Kumar et al, 2022). It is estimated that 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Agents targeting B-cell maturation antigen (BCMA), including antibody-drug conjugates (ADCs), chimeric antigen receptor (CAR) T-cell therapies, and bis... |
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Pathology and Oncology Expert Perspectives in the Management of Triple-Negative Breast Cancer: Case Explorations and Answers to FAQs
STATEMENT OF NEED
Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for approximately 10% to 15% of breast cancer diagnoses and is characterized by the absence of estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2 (HER2). TNBC is more common in Black women and in women under the age of 40 (ACS, 2023). Compared with other subtypes of invasive breast cancer, TNBC has high rates of metastasis and a poor prognosis. Due to the lack ... |
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Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults
STATEMENT OF NEED
Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w... |
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Current Standards and New Directions in the Treatment of Acquired Thrombotic Thrombocytopenic Purpura
STATEMENT OF NEED
Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy with a rapid onset and progression and a mortality rate of 10% to 20% with prompt treatment. Onset of aTTP is characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and a constellation of associated symptoms including hemorrhage, neurologic and renal manifestations, cardiac abnormalities, and mesenteric ischemia (Joly et al, 2017). Survivors of f... |
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Operation Game- A Patient’s Journey Through HeFH: Diagnosis and Management
Target Audience
This activity has been designed to address the educational needs of cardiologists, cardiology nurses, lipid specialists, and primary care clinicians, including internists, pharmacists, nurses, nurse practitioners, PAs, and dietitians. It may also benefit other healthcare providers who manage patients with hypercholesterolemia.
Program Overview
Nonstatins are an essential therapy for lowering low-density lipoprotein cholesterol (LDL-C) levels in high-risk patients, such as ... |
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Pulmonary and Critical Care Medicine 2024 - LIVE STREAMING
Comprehensive Updates for State-of-the-Art Evaluation, Diagnosis, and Treatment
This comprehensive live streaming online course, which is among the highest-rated Harvard Medical School CME courses, provides education and updates to optimize your care of patients with:
• Sepsis
• ARDS
• Sarcoidosis
• IPF
• Bronchiectasis
• Cystic fibrosis
• Lung nodules
• Lung cancer
• GERD
• Pleural disease
• Pneumonia
• Tuberculosis
• Thromboembolism
• Chronic cou... |
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Advancing the Care of Patients Living with EGPA Through Multidisciplinary, Patient-Focused Care
Target Audience
This educational activity is intended for rheumatologists, allergists, immunologists, pulmonologists, and specialty advance practice clinicians who care for patients with EGPA.
Program Overview
The comprehensive program provides up-to-date information regarding EGPA"its recognition, diagnosis, and treatment"and incorporates the patient perspective to raise awareness of patients’ needs, heighten urgency, and, ultimately, educate on the disease. The program will ... |
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The Safety of Opioid Use in Chronic Obstructive Pulmonary Disease
This session will evaluate the safety of opioid therapy among patients with chronic obstructive pulmonary disease (COPD). The session will cover existing safety and effectiveness evidence from clinical trials, and present the latest data from observational studies. The presentation will include a discussion of the strengths and disadvantages of observational study designs along with implications for future practice.
Approximately 15.7 million Americans (6.4%) currently are diagnosed with CO... |
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Geographic Atrophy: Rapid Response from ARVO
Geographic atrophy (GA) is a pathological deterioration of the retina seen in the late stages of age-related macular degeneration (AMD). It affects 20% of people with AMD, and its prevalence increases exponentially with age. Until recently, there were no treatment options for GA, but investigation into the complement system and its role in the pathogenesis of GA has led to targeted therapies that have revolutionized the treatment paradigm. Because of the recent approval of one of these therapi... |
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INFORM: Information Needed for Optimal Regulation of Mycophenolate- A REMS Activity
Target Audience
The target audience for this initiative includes obstetricians, gynecologists, primary care physicians, physician assistants, nurse practitioners, pharmacists, and care team members involved in the treatment of women across their reproductive lifespan who may have been prescribed mycophenolate products.
Program Overview
Clinicians who work with women of childbearing age who are, or will be, taking mycophenolate must ensure that their patients receive appropriate counseling... |
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A Class Act in Glaucoma Management: Differentiating Rho Kinase Inhibitors From the Pack
Medical management of glaucoma primarily focuses on lowering intraocular pressure (IOP) by decreasing aqueous production, reducing episcleral venous pressure, and/or increasing uveoscleral and trabecular outflow. Recently approved agents have expanded treatment options beyond the traditional mainstays of prostaglandin analogues and β-blockers, engaging Rho kinase (ROCK) inhibition to improve outcomes for patients with glaucoma. In this CE monograph, experts in the field will review the clinic... |
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EGPA Expert Exchange " A Podcast Series on Eosinophilic Granulomatosis With Polyangiitis
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg-Strauss syndrome, is a rare form of vasculitis that primarily affects the small blood vessels. Individuals diagnosed with EGPA commonly have a history of asthma and/or allergies. Eosinophilic inflammation associated with EGPA can lead to injury in multiple organ systems, including the sinuses, lungs, gastrointestinal system, heart, nervous system, and kidneys. Accurate diagnosis and treatment are critical to minimize g... |
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Eosinophilic Esophagitis: Experts Address Your Burning Questions
Eosinophilic esophagitis (EoE) is a chronic type 2 helper (Th2)-mediated inflammatory disorder that is characterized by symptoms of esophageal dysfunction and esophageal inflammation with intraepithelial eosinophils. Once considered rare, EoE is a relatively new disease that is now commonplace and affects both children and adults. When left unmanaged, EoE can impact a patient’s ability to eat properly, leading to food impaction and increased medical expenses. Recent data indicate that many c... |
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Eyeing the Options for Treating Meibomian Gland Dysfunction and Dry Eye Disease
Dry eye disease (DED) is highly prevalent but frequently underdiagnosed and subsequently undertreated. Studies have demonstrated that meibomian gland dysfunction (MGD) is a leading cause of the development and progression of evaporative DED, caused by a deficient tear film lipid layer that leads to increased tear evaporation. New and emerging treatments with novel mechanisms of action are being investigated that manage the signs and symptoms of DED associated with MGD and offer the potential f... |
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Parenteral Nutrition Solutions: Developing a Playbook for the Multidisciplinary Team
In these symposium highlights, a multidisciplinary panel of experts discuss a range of topics, including the role of indirect calorimetry, protein requirements, intravenous lipid emulsions, and the nutrition support team. Also highlighted are a real-world patient case and the questions and answers/panel discussion. An accompanying infographic on the importance of the nutrition support team and how to organize one can be downloaded and shared with your team. |
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Warm Autoimmune Hemolytic Anemia (wAIHA)
Target Audience
This activity has been designed to meet the educational needs of physicians specializing in hematology and hematology-oncology. Other members of the care team may also participate.
Program Overview
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing ... |
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Optimizing Outcomes in ALS: Best Practices in Screening, Diagnosis, and Treatment
"Optimizing Outcomes in ALS: Best Practices in Screening, Diagnosis, and Treatment" is a modular continuing education series led by Dr. Richard Bedlack, a nationally recognized ALS expert. This self-navigation program focuses on amyotrophic lateral sclerosis (ALS), providing healthcare professionals with valuable insights and evidence-based strategies to enhance outcomes in ALS care. Participants have the flexibility to choose their own track and explore various modules, covering cli... |
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NeuroRehabilitation 2024 - LIVE STREAMING
Comprehensive Neurorehabilitation Update
Cutting-edge strategies, updates, and best practices for state-of-the-art rehabilitation
In this course, which is among the highest-rated Harvard Medical School CME courses, many of the country’s most experienced and committed neurorehabilitation experts will present cutting-edge clinical interventions, the latest findings, practical education, and hands-on methods to further your expertise in guiding your patients with stroke, SCI, TBI, brain t... |
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Is It Safe? Safety Surveillance through the Antiretroviral Pregnancy Registry
Is It Safe? Safety Surveillance through the Antiretroviral Pregnancy Registry
Release Date: June 2, 2023
Expiration Date: June 2, 2024
Estimated Time to Complete: 1.25 hour
VIEW ACTIVITY
Clinical Gap and Educational Need
Antiretroviral therapy should be initiated for all persons with HIV who are pregnant regardless of CD4 count according to current guidelines. There is often minimal data available to make recommendations, however, for use in pregnancy. One key consideration is... |
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Comprehensive Sterile Compounding
June 6th - 8th, 2024
COMPREHENSIVE STERILE COMPOUNDING is an accredited 3-day, 20-hour (2.0 CEUs) practice-based course designed for pharmacists and technicians who are experienced in compounding.
Physicians and other healthcare professionals are welcome to attend. This course will also provide initial aseptic training for pharmacists and technicians required by their state board of pharmacy to compound sterile preparations.
Participants are instructed in the proper aseptic techniques... |
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Neonatal Intensive Care Nursing Exam Review (Live Webinar) - Boston, MA
Course Description
This course is designed to supplement study materials for the NCC certification exam to obtain the RNC-NIC designation and the AACN certification exam to obtain the CCRN-neonatal designation. The course will focus on core concepts that are essential for caring for high-risk newborns. Preparation is recommended prior to participation in this course.
Program Learning Outcomes
This program prepares the learner to:
1. Review the core components covered by the exam throug... |
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Meeting Milestones in nAMD and DME Management: What's New?
Anti-vascular endothelial growth factor (VEGF) therapy has revolutionized treatment paradigms for neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME). However, these agents are associated with a high treatment burden because of the injection frequency, and a substantial number of patients do not adhere to their treatment schedules, resulting in suboptimal response to therapy. To address these issues, new dosage regimens and surgical drug delivery approaches hav... |
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WEBINAR: The GRAS is Not Always Greener: Providing Toxin-free Drug Therapy to Animal Patients
Pharmacists and pharmacy technicians often are the last line of defense in recognizing and preventing potential animal poisoning. Unfortunately, pharmacists and pharmacy technicians traditionally are trained only in human toxicology. To provide competent and confident pharmaceutical care to non-human species, pharmacists and pharmacy technicians must possess a working knowledge of species-specific susceptibilities to toxins. Factors that affect the risk of toxicity vary greatly among species; ... |
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Disparities in Ovarian Cancer: Increasing Awareness to Improve Risk Assessment and Outcomes
Ovarian cancer is the most common cause of cancer death in women with gynecologic malignancy and the fifth leading cause of cancer death in the US. Although the incidence of ovarian cancer is higher among White women than Black women, studies have identified disparities in assessment, care and outcomes seen among Black women with ovarian cancer. It has been shown that outcomes in clinical oncology can be improved when care is delivered by high performance teams. This activity was designed by ... |
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Managing Thyroid Eye Disease: Rapid Response From ENDO
For a timely diagnosis and optimal management of thyroid eye disease (TED), a multidisciplinary team of endocrinologists, ophthalmologists, oculoplastic surgeons, as well as other healthcare professionals is essential. Early diagnosis of TED through imaging and clinical assessment is imperative to allow for the timely initiation of therapeutic strategies that limit disfiguration and reduce the potential for vision loss. The recent updates to guidelines for the management of TED, along with the... |
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Build Your Own Case Study | Obesity: Treating the Whole Patient
Activity Description
Obesity is a chronic, progressive, relapsing disease that impacts health and quality of life. In individuals with obesity, there are many contributors to its development and persistence, including lifestyle, social, and economic factors. If left untreated, obesity can be a primary driver of serious health consequences. By treating obesity first, complications arising from obesity may improve or resolve. Given the severity of the disease, there is a need for clinicians in ... |
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Answering the Call in Severe Asthma Expanding Roles for Biologic Treatment Regimens
This enduring Call-a-Colleagueâ„¢ educational program will guide attendees through the long-term management of severe asthma. Expert faculty will provide actionable recommendations on evaluation strategies that consider underlying mechanism of disease, data on newer biologic treatment options, and most importantly, the use of these therapies in current day practice. Interspersed throughout the program are brief Call-a-Colleagueâ„¢ video calls in which faculty consult with their specialist coll... |
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From Evidence to Empowerment: Supporting Bottle-Feeding Parents with Emerging Science
Most infants will receive a bottle at some point in their first year, whether breastmilk or formula. However, some experts have concerns about the impact of bottle feeding and how it differs from breastfeeding. Some research suggests that bottle feeding may increase the risk of overfeeding and rapid weight gain. Current research explores how new bottle-feeding techniques may help avoid these potential risks.
Join Dr. Alison Ventura, pediatric nutrition researcher, and Jadah Parks Chatterje... |
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How I Treat Paroxysmal Nocturnal Hemoglobinuria (PNH)
In this point-counterpoint digital activity, two expert faculty discuss and debate treatment selection for patients with PNH through case-based scenarios. Faculty review mechanisms of action, clinical trial data, and real-world evidence supporting divergent treatment strategies for the presented cases. How do the experts make their initial treatment selections? Why might they choose a C5 inhibitor or a C3 inhibitor? How do they assess response to treatment, and what do they do when treatment r... |
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Internal Medicine Comprehensive Review and Update 2024 - LIVE STREAMING
Comprehensive, Evidence-Based Updates for Internal Medicine and Its Subspecialties
This program, the 64th annual Internal Medicine Update from the leading clinical faculty of Harvard Medical School and Massachusetts General Hospital, provides comprehensive, high-yield instruction to ensure clinicians are current with the latest evidence and best practices to optimize patient care.
This program covers the breadth of Internal Medicine subspecialties, including:
• Cardiovascular Medicine
â€... |
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Lifestyle Medicine: Tools for Promoting Healthy Change - LIVE STREAMING
State-of-the-Art Approaches to Help Patients Initiate and Sustain Health-Promoting Behaviors
Lifestyle Medicine will be held online this year, using live streaming, electronic Q&A, and other remote learning technologies.
Overview
This immersive two-day course offers state-of-the-art strategies to guide patients to healthier lives. Education includes evidence-based strategies, tools and techniques to effect healthier changes in patients (and ourselves), including weight loss, exerci... |
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Neuromyelitis Optica Spectrum Disorder: Updates on Diagnosis and Treatment Management
Neuromyelitis optica spectrum disorder (NMOSD) is a rare, relapsing, autoimmune disease of the central nervous system that is characterized by inflammation in the optic nerve and spinal cord. Unfortunately, early stages of NMOSD are frequently misdiagnosed as multiple sclerosis or other diseases. Diagnosis is typically based on the presence of key clinical characteristics"aquaporin-4 (AQP4) antibody status and magnetic resonance imaging. The application of newer diagnostic criteria may as... |
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15th Annual Essentials in Primary Care Summer Conference
Continuing Education Company has been organizing its Primary Care Conference Series for over 30 years. The Essentials in Primary Care Summer Conference is designed to update primary care clinicians in rapidly changing therapeutic areas. The emphasis is on practical and useful information for clinical practice. Join us this July when we hold the 15th Annual Essentials in Primary Care Summer Conference.
This conference will be held at the Hammock Beach Resort in Palm Coast, Florida. Located n... |
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Pathways for Optimal Sequencing, Rapid Initiation, and Titration of Therapy in Patients with Heart Failure
Many patients with heart failure (HF) do not receive foundational treatment although these therapies reduce morbidity and mortality risks. The initiation and optimization of guideline-directed medical therapies (GDMT) can be challenging, but clinical practice guidelines and algorithms are available to assist.
Navigate through this interactive self-directed CME activity to apply the most recent clinical trial data and guidance to patient-specific factors seen in real-world practice. Expert p... |
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Call to Action for Health Equity: Racial Disparities in the Care of Patients with Cardiometabolic Disease
Cardiovascular disease is the leading cause of death for adults in the US. However, patients from minority populations with cardiovascular disease have disproportionately poor health outcomes and are particularly vulnerable to health disparities. Racial inequities in health also result in higher risk-burden in minority groups for metabolic syndromes such as Type 2 (adult-onset) diabetes, which increase the risk of cardiovascular disease. Health disparities in cardiometabolic care predominantly... |
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Reducing Risks in Asthma: Mucus Plugs and Airway Obstruction
Target Audience
The educational design of this activity addresses the needs of pulmonology and clinical immunology clinicians who manage patients with severe asthma who are at risk for mucus plugs.
Program Overview
This Point-of-Care 201 program has been designed to educate and promote critical thinking through a discussion-based format that is accompanied by 3-dimensional animation. Expert faculty examine various sides of key clinical issues in asthma"including exploration of the pa... |
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Veterinary Compounding Essentials
July 19th - 20th, 2024
VETERINARY COMPOUNDING ESSENTIALS is an accredited 15-hour (1.5 CEUs) practice-based course that introduces pharmacists, technicians, and marketers to veterinary pharmacy compounding. The program provides fundamental techniques for effectively growing the veterinary compounding practice, including calculations, proper safety practices, hands-on compounding, and marketing.
Upon completion of this program, the participant will be able to:
• Demonstrate knowledge o... |
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Understanding Fibromyalgia
Understanding Fibromyalgia is an online nurisng CE course intended to help healthcare professionals recognize the symptoms of fibromyalgia and diagnose it early. It will discuss potential causes, signs and symptoms, criteria for diagnosis, and treatment options. |
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The PrEP Journey Charting the Course Through HIV Prevention
HIV prevention with preexposure prophylaxis (PrEP) is an essential tool for clinicians to help end the HIV epidemic. In this case-based interactive activity, you will learn the basics of assessing HIV risk, conversing with patients about sexual health, and providing PrEP, from initiation to monitoring and follow-up. Then, more challenging cases will illustrate the nuances of providing PrEP based on patient characteristics and preferences. Prof Daniel Richardson and nurse practitioner Shauna Ap... |
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Professionalism: Communicating with the Health Care Team
This course proposes practical definitions of professionalism and identifies patterns of questionable professional behavior. It shows how to improve professional behavior and communication among different members of the health care team with a focus on power differentials, generational differences, and how these interactions directly connect to patient care.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Communicate effectively ... |
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Case Studies in Hereditary Angioedema: Moving Beyond Crisis to Long-Term Prevention
Hereditary angioedema (HAE) is an autosomal dominant condition that causes recurring, unpredictable, and potentially fatal attacks resulting in a profound disease burden and diminished health-related quality of life (QoL). Recent advances have led to new therapies for HAE, including long-acting prophylactic therapies that have improved efficacy, tolerability, and convenience, compared to earlier treatments. Many health care providers are unaware of HAE and its diagnosis, particularly the diffe... |
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Hot Topics in Blood-based Cancer Screening: Key Information on Multi-Cancer Early Detection from 2023 Spring Oncology Meetings
Early detection of cancer is essential to reducing the significant burdens associated with it. When cancer is detected at earlier stages, treatments can be initiated sooner, resulting in improved outcomes, reduced morbidity and mortality, and better quality of life. While the implementation of current screening guidelines has resulted in an overall reduction in cancer deaths, only 25% of cancers are diagnosed using traditional screening modalities, leaving much room for improvement. Blood-base... |
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Dialogues about FOP: What Patients Wish More Doctors Knew to Enhance Early Recognition and Management
Target Audience
The educational design of this activity addresses the needs of the primary audience of PCPs, pediatricians, dermatologists, endocrinologists, occupational therapists, oncologists, general practice NPs and PAs, specialist NPs and PAs, and the secondary audience of orthopedists, bone specialists, rheumatologists, pediatric rheumatologists, genetic counselors, and dentists.
Statement of Need/Program Overview
Fibrodysplasia ossificans progressiva (FOP) causes abnormal bone for... |
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Multidisciplinary Strategies to Prevent Hospitalization in Patients with Worsening Heart Failure
Despite guideline-directed medical therapy, many patients with heart failure (HF) with reduced ejection fraction continue to experience worsening HF and hospitalizations. As such, it is incumbent upon clinicians to improve familiarity and competence with available therapies and clinical trial data that may guide patient selection to individualize and optimize therapy for patients with HF. In this interactive infographic, clinicians can access real-world strategies and expert insights to improv... |
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Introduction and Advanced/Interventional & Regenerative Medicine Musculoskeletal Ultrasound
The Introduction to Musculoskeletal Ultrasound & Advanced, Interventional and Regenerative Medicine Musculoskeletal Ultrasound Live Training Course provides participants a comprehensive introduction to musculoskeletal ultrasound and interventional/regenerative medicine techniques. Taught by leading musculoskeletal ultrasound experts, this course incorporates comprehensive lectures on upper and lower extremity applications for diagnostic and ultrasound-guided injection/aspiration techniques... |
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Introduction and Advanced/Interventional & Regenerative Medicine Musculoskeletal Ultrasound with Cadaver Lab
The Introduction and Advanced/Interventional & Regenerative Medicine Musculoskeletal Ultrasound Live Training Course is the most comprehensive MSK ultrasound course in the industry, beginning with foundational diagnostic MSK ultrasound applications and building to advanced interventional and regenerative medicine applications.
This course is taught by leading musculoskeletal ultrasound experts and incorporates comprehensive lectures covering upper and lower extremity applications, ultra... |
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Introduction and Advanced/Interventional & Regenerative Medicine Musculoskeletal Ultrasound
The Introduction to Musculoskeletal Ultrasound & Advanced, Interventional and Regenerative Medicine Musculoskeletal Ultrasound Live Training Course provides participants a comprehensive introduction to musculoskeletal ultrasound and interventional/regenerative medicine techniques. Taught by leading musculoskeletal ultrasound experts, this course incorporates comprehensive lectures on upper and lower extremity applications for diagnostic and ultrasound-guided injection/aspiration techniques... |
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Top 3 Differentials in Radiology
Program Description:
This program is intended for practicing radiologists and radiology trainees as a comprehensive and practical case-based radiology review. All subspecialties and imaging modalities will be covered with lectures divided into the following sections: neuroimaging, musculoskeletal imaging, gastrointestinal imaging, genitourinary imaging, ultrasound imaging, cardiothoracic imaging, pediatric imaging, breast imaging, vascular & interventional radiology, and nuclear medicine. Lec... |
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Advanced and Interventional & Regenerative Medicine Musculoskeletal Ultrasound
The Advanced, Interventional & Regenerative Medicine Musculoskeletal Ultrasound Live Training Course is taught by leading experts in the field of MSK ultrasound and incorporates comprehensive lectures, interactive case presentations, and live PRP procedural demonstrations for various pathological conditions on actual patients.
Extensive hands-on scanning sessions feature a 3:1 participant to faculty ratio with live standardized patient models and inanimate phantoms PLUS a four (4) hour ... |
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Clinical Consults in Severe Asthma: New Approaches to Targeted Therapy
As management options for the treatment of severe asthma continue to expand with the addition of effective biologic therapies, physicians often consult colleagues for advice on complex cases or challenging issues. This 3-episode Phone-a-Friend series features 3 expert physicians asking and answering questions related to the management of severe asthma. The series will cover a variety of topics, including patient symptom assessment; disease phenotyping; rationale for treatment escalation or swi... |
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